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, a discrete period of intense fear or discomfort in which 4 (or more) of the following symptoms develop abruptly and reach a peak within 10 minutes: (1) palpitations, pounding heart, or accelerated heart rate; (2) sweating; (3) trembling or shaking; (4) sensations of shortness of breath or smothering; (5) feeling of choking; (6) chest pain or discomfort; (7) nausea or abdominal distress; (8) feeling dizzy, unsteady, lightheaded, or faint; (9) derealization (feelings of unreality) or depersonalization (being detached from oneself); (10) fear of losing control; (11) fear of dying; (12) paresthesias (numbness or tingling sensations); (13) chills or hot flushes.
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 This category indicates episodes a prominent and relatively persistent depressed or dysphoric mood that usually interferes with daily functioning and should include 4 of the following symptoms: increased fatigue, change in sleep, change in appetite, loss of interest in usual activities or decrease in sexual drive, feelings of guilt or worthlessness, suicide attempt and slowed thinking or impaired concentration.
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This drug is indicated for treatment of major depressive disorder and its major depressive episode was established in 6- week controlled trials of outpatient whose diagnoses corresponded mostly closely to DSM-III category of major depressive disorder.