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Hydroxyurea is used for:Reducing the number of painful episodes and blood transfusions needed by adults with sickle cell anemia experiencing recurrent episodes associated with moderate to severe pain. It may also be used for other conditions as determined by your doctor.
Hydroxyurea is an antineoplastic agent. Exactly how it works is unknown, but it is thought to increase the ability of deformed red blood cells to change shape, which may lessen pain associated with sickle cell anemia.
Treatment for:
* Polycythemia vera
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* Sickle-cell disease (breaks down cells that are prone to sickle, as well as increasing fetal hemoglobin content)
* AIDS as an adjunct to ddI in combination antiretroviral therapies
* Biochemical research as a DNA replication inhibitor that causes ribonucleotide depletion and results in DNA double strand breaks near replication forks (see DNA repair)
Moderate to severe psoriasis (slows down the rapid division of skin cells)
Do NOT use Hydroxyurea if: * you are allergic to any ingredient in Hydroxyurea
* you have severe bone marrow depression, low white blood cell counts, low blood platelet levels, or severe anemia
Contact your doctor or health care provider right away if any of these apply to you.
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