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public Breath may help in disease diagnosis Your breath can reveal more than what you ate or drank, it may provide a very inexpensive method of diagnosing any disease you might be suffering from, researchers say. The breath potentially contains trace of more than 1000 compounds even though you might see only water vapour coming out of your mouth on a cold winter day, they say. A team of researchers led by Jun Ye has demonstrated that an optical technique for simultaneously identifying tiny amount of a broad range of molecules in breath has the potential of enabling a fast, low cast screen tool for disease. "It is exciting to imagine the potential of analysing all major biomarkers in one's breath at once," says Ye, a physicist at JILA, a joint institute of National Institute of Standards and Technology (NIST) and the University of Colorado at Boulder. Giving an example, he says nitric oxide can indicate asthma, but it also appears in breath with many other lung diseases, including chronic obstructive pulmonary disease, cystic fibrosis and bronchiectasis. "However, if we simultaneously monitor nitric oxide, carbon monoxide, hydro-peroxide, nitrites, nitrates, pentane, and ethane, all important biomarkers for asthma, we can be much more certain for a definitive diagnosis of this important disease," he adds. Existing methods for detecting trace amounts of molecules from the breath, the researchers say, are either bulky, slow, limited to specific molecules, unable to distinguish very well between multiple compounds or inaccurate at measuring their concentrations.
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