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The lack of effect of cinacalcet on the pharmacokinetics of R- and S-warfarin and the absence of auto-induction upon multiple dosing in patients indicates that cinacalcet is not an inducer of CYP2C9 in humans.
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Allow the patch to remain in place until the desired anesthetic effect is produced but not for longer than 15 minutes.
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These include increases in heart rate and blood pressure, which present risks of particular concern for people with circulatory problems or heart disease; and other symptoms such as muscle tension, involuntary teeth clenching, nausea, blurred vision, faintness, and chills or sweating.
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Time-to-peak concentration (Tmax) was also delayed (4.3 h versus 3.3 h) and terminal half-life was decreased (2.4 h versus 9.0 h) under fed conditions compared to fasted.
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Some changes are more serious than others, but no matter what the problem, there are things you can do to protect your vision.
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Mixed from the ampul at concentrations of greater than 10В mg/mL BREVIBLOC has, however, been well tolerated when administered via a central vein.
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Factors that increase the risk of narcosis include cold temperatures, rapid descent, anxiety, alcohol, sedatives, fatigue, and carbon dioxide excess.
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Intramuscular injections should not be made into the lower and mid-third of the upper arm.
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Treatment of a patient with toxic manifestations consists of assuring and maintaining a patent airway and supporting ventilation (respiration) as required.

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Ideally, the family should be supportive without perpetuating their loved one’s symptoms.
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The extent to which SSRI-TCA interactions may pose clinical problems will depend on the degree of inhibition and the pharmacokinetics of the SSRI involved.
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Hypotheses about development are tested using genetic and embryo manipulations, e.g., lesions, transplantations, and transgenic organisms.
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An Ace wrap may be used for compression.
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A general surgeon performs the operation.
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This pain can occur at the front outside part of the lower leg, including the foot and ankle (anterior shin splints) or at the inner edge of the bone where it meets the calf muscles (medial shin splints).
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Pegvisomant reduced IGF-I levels at all doses compared to treatment with the placebo.
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Clinical trials are an important way in which the medical and healthcare professionals get information about how well a treatment works, how safe it is, the right dose to use, and how it compares with other treatments available.
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Pneumonia: In young, healthy adults, the prognosis for pneumonia is good with appropriate treatment.

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If any of these reactions occurs in patients receiving lomefloxacin, the drug should be discontinued and appropriate measures instituted.
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There is no cure for locked-in syndrome, nor is there a standard course of treatment.
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Unlike x-rays and some other tests, echocardiography doesn't involve radiation.
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In most cases, life-long, suppressive medication will need to be taken.
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Depression represents a burden for the person and his or her family.
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Pentazocine passes the placental barrier.
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Pregnancy Category C. Sumatriptan has been shown to be embryolethal in rabbits when given daily at a dose approximately equivalent to the maximum recommended single human subcutaneous dose of 6В mg on a mg/m2 basis.
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The only test which can fully confirm the diagnosis of prostate cancer is a biopsy, the removal of small pieces of the prostate for examination by a pathologist.
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Ibandronate may help lower the chances of breaking bones (fractures).

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Many children diagnosed with the disorder benefit from rehabilitation therapies and educational interventions, and go on to lead normal lives with few limitations.
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Media type: PhotoMedia file 3: A type of ear protection for water sports such as skiing, windsurfing, wakeboarding, or parasailing.
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Rest, ice, and elevate your arm or leg.
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Adult female Dracunculus worms emerge from the skin of Infected persons annually.
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Cervical fluid qualities are also charted throughout a woman’s cycle.
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IN THIS ARTICLEHand Injury OverviewHand Injury CausesHand Injury SymptomsWhen to Seek Medical CareExams and TestsHand Injury TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upPreventionOutlookSynonyms and KeywordsAuthors and EditorsAuthors and EditorsAuthor: Chad Tarr, MD, Staff Physician, Department of Emergency Medicine, Emory University School of Medicine.
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At doses estimated to be 1.8 times (900 mg/m2) and 0.49 times (240 mg/m2) the daily human dose of 800 mg (492 mg/m2) in the rat and rabbit, respectively, no evidence of fetal terata was found.
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Several major health organizations recommend iron supplementation during pregnancy to help women meet their iron requirements.
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Based on clinical monitoring (including serum estradiol levels and vaginal ultrasound results) subsequent dosing should be adjusted according to individual patient response.

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Azole antifungal agents — Ketoconazole and itraconazole are potent CYP3A inhibitors and have been shown in vivo to increase plasma alprazolam concentrations 3.98 fold and 2.70 fold, respectively.
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Studies both in experimental motion sickness and in naval cadets at sea have found that ginger, taken in advance, has reduced the symptoms of motion sickness.
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In mild cases, withdrawal symptoms may include unpleasant feelings.
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Most often, pericarditis is self-limiting with medical care directed toward controlling the major symptom of pain.
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In about half of all cases, an affected person inherits a STAT3 mutation from an affected parent.
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Antidiabetic drug requirements, i.e., insulin, may be altered in association with the use of Diethylpropion hydrochloride and the concomitant dietary regimen.
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Members of these families may be at increased risk for sudden cardiac arrest.
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The World Health Organization (WHO) has officially declared the 2009 swine flu to be a pandemic.
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The following adverse reactions should be kept in mind whenever corticosteroids are given by rectal administration.

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The effects observed in mechanistic experiments in vitro and studied in intact animals and man are compatible with this mechanism of action and are typical of the class.
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Generally, even at night in most places, headlights and streetlights provide enough light to see.
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You insert this into your vagina before sex so it covers your cervix.
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Most individuals with type 1 Pfeiffer syndrome have normal intelligence and a normal life span.
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Contains sodium bisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people.
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In these studies, 28% of patients receiving Anafranil had a weight gain of at least 7% of their initial body weight, compared with 4% of patients receiving placebo.
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For this reason, doctors will use increased levels of oxygen but maintain levels below 100% in ARDS.
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It is best to wait until you are certain the skin is completely dry.
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For some women who are done having children or do not want children, endometrial ablation is performed.

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Bleeding may occur for a couple of weeks after an IUD is placed.
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Isotretinoin is a teratogen - it is highly likely that it will cause birth defects if taken during pregnancy.
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Some systems of yoga such as Kundalini yoga start with meditation while others such as Kriya yoga start with breathing techniques.
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Because use of these drugs is rarely a matter of urgency, their use during this period should almost always be avoided.
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Less commonly, a person may have generalized aches or a low-grade fever.
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Information about clinical trials is available from the NCI Web site.
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Lancet 354 (1999) 2132-2133; Dresel et al.
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ALS is one of a group of diseases known as motor neuron diseases.
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A condition called vascular rosacea causes persistent flushing and redness.

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Thalassemias affect both males and females.
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Since mineralocorticoid secretion may be impaired, salt and/or a mineralocorticoid should be administered concurrently.
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Meanwhile, population education remains the mainstay in trying to decrease the risk of heart disease and the subsequent development of pulmonary edema and heart failure.
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Self-Care at HomeMake sure that the bleeding is coming from the vagina and is not from the rectum or in the urine.
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Blood tends to pool by gravity in the lowest parts of the body.
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Primary efficacy variable was twice-daily reflective patient scoring of four nasal symptoms (rhinorrhea, nasal stuffiness/congestion, nasal itching, and sneezing) and four non-nasal symptoms (itching/burning eyes, tearing/watering eyes, redness of eyes, and itching of ears/palate) on a four point scale (0=none, 1=mild, 2=moderate, and 3=severe).
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Because diet may play a role in symptoms associated with low blood sugar, avoid candy, soda, and other sugary foods, especially in the week before your period.

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Based on the 400 mg/5 mL strength, at the usual recommended doses, adult patients would receive a total of 470 mg/day (20.4 mEq) of sodium.
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Nitrogen Narcosis SymptomsSymptoms include light-headedness, inattention, difficulty concentrating, poor judgment, anxiety, decreased coordination, hallucinations, and coma.
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In general, NIDA-supported research shows that use of any club drugs can cause serious health problems and, in rare instances, even death.
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Information about ongoing clinical trials is available from the NCI Web site.
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If the ratio is low, then cancer and pancreatitis are potential causes.
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The objective response rate on the Gemzar plus cisplatin arm was 26% compared to 10% with cisplatin (Fisher’s Exact p<0.0001, two–sided).
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The doctor will make sure that symptoms are not due to an intestinal blockage and will look for the cause of the condition, such as an underlying illness.

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Each person’s response to medication varies and changes with time, and IOP control may deteriorate despite the use of multiple medications.
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Frequent washing of the hands, especially before eating, after using the toilet, after spending time in a crowded public place, or after petting animals, can minimize exposure to bacteria or viruses that can result in fever.
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Pancreas failure: The pancreas may become so severely damaged that it is unable to carry out its normal functions.
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Fasting insulin decreased more for XENICAL than placebo (-39 vs -16 pmol/L) from randomization to 1 year in the population with abnormal baseline values (≥120 pmol/L).
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Rare cases of hemolytic uremic syndrome, thrombotic thrombocytopenic purpura, and pulmonary embolus have been reported primarily among patients who had been receiving concomitant cyclosporine or tacrolimus for management of transplant rejection or graft-vs-host disease.

When daily doses of sulfasalazine 2 g and weekly doses of methotrexate 7.5 mg were coadministered to 15 rheumatoid arthritis patients in a drug-drug interaction study, the pharmacokinetic disposition of the drugs was not altered.
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Caloric restriction and increased physical activity not only help diabetic patients maintain normal blood glucose values, they also can delay or prevent some people from developing diabetes in the first place.
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Metoclopramide Injection, USP is degraded when admixed and frozen with Dextrose-5% in Water.

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The discontinuation rate in controlled clinical trials, because of adverse events, was up to 10% for patients treated with etodolac.
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One method of defining cardiomyopathy is based on the official definition by the American Heart Association (see below), which are broken into two categories, primary and secondary.
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Established in 1987, the Clearinghouse provides information about diseases of the kidneys and urologic system to people with kidney and urologic disorders and to their families, health care professionals, and the public.

Fosphenytoin sodium injection has important differences in administration from those for parenteral phenytoin sodium (see below).
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Metformin was effective for both men and women, but it was least effective in people aged 45 and older.
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Fexofenadine hydrochloride, the major active metabolite of terfenadine, is an antihistamine with selective peripheral H1-receptor antagonist activity.

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The activity of these pathways slowly increases to maximal levels by one year of age.
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The risk of developing parkinsonian-like side effects increases with ascending dose.
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The injection is taken once a day, and the dose is adjusted according to weight: 5 mg for weights less than 110 lbs (50 kg), 7.5 mg for weights 110–220 lbs (50-100 kg), and 10 mg for weights greater than 220 lbs(100 kg).
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If in charge of motor function, the area is called the motor cortex.
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In rats made febrile by the subcutaneous administration of brewer's yeast, fenoprofen produces antipyretic action.

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Teratogenic effects characteristic of corticosteroids were noted in both species.
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IN THIS ARTICLELife-Threatening Skin Rashes OverviewLife-Threatening Skin Rashes CausesLife-Threatening Skin Rashes SymptomsWhen to Seek Medical CareExams and TestsLife-Threatening Skin Rashes TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upPreventionOutlookSynonyms and KeywordsAuthors and EditorsPictures Adult Skin Problems - Slideshow Gallery of Skin Problems Pictures and Images Collection Pictures of Childhood Skin Problems - Slideshow OutlookThese disorders pose a serious risk for death if they do not get treated.

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For example, a child may not want to use the toilets at school or may not want to interrupt enjoyable activities, so he or she ignores the bodyВ’s signal of a full bladder.
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The history of yoga may go back anywhere from five to eight thousand years ago, depending on the perspective of the historian.
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During an acute infection, certain viruses can be isolated through culture or detected by nucleic acid amplification, or PCR (a technique that makes multiple copies of the viral genetic material, making it easier to detect).
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A Pharmacy Bulk Package is a container of a sterile preparation for parenteral use that contains many single doses.
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Symptoms associated with horse chestnut poisoning may include vomiting, diarrhea, headache, confusion, weakness, muscle twitching, poor coordination, coma, or paralysis.
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Fiberoptic tubes are then used to carry the laser light to the cancer cells, where the drug becomes active and kills the cells.

Previous PageGlossaryNext Page »Next: Next Steps » Printer-Friendly Format |  Email to a Friend Privacy Policy GI Disorders Get the latest treatment options.
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Smoking and some medical conditions such as diabetes and high cholesterol also promote plaque formation and narrowing of the arteries.

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Bladder catheterization may be a temporary or a permanent solution for urinary incontinence.
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The catabolism of thioguanine and its metabolites is complex and shows significant differences between humans and the mouse.
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A fertility and reproductive performance study performed in female rats revealed that anagrelide hydrochloride at oral doses of 60 mg/kg/day (360 mg/m2/day, 49 times the recommended maximum human dose based on body surface area) or higher disrupted implantation and exerted adverse effect on embryo/fetal survival.
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Hyaluronidase increases the leakiness of connective tissue by breaking down hyaluronan.
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The overstimulation of this system, which normally responds to natural behaviors that are linked to survival (eating, spending time with loved ones, etc.

Indomethacin exists in the plasma as the parent drug and its desmethyl, desbenzoyl, and desmethyldesbenzoyl metabolites, all in the unconjugated form.
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Wild animals carrying the tapeworm could set up the transmission cycle and expose animals not already infected.
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Synercid, dalfopristin, and quinupristin were tested in the bacterial reverse mutation assay, the Chinese hamster ovary cell HGPRT gene mutation assay, the unscheduled DNA synthesis assay in rat hepatocytes, the Chinese hamster ovary cell chromosome aberration assay, and the mouse micronucleus assay in bone marrow.

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Antibiotics are usually not required in closed head injuries.
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A more serious form of diarrhea can occur during or up to 2 months after the use of antibiotics.
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Catecholamine-depleting drugs (e.g., reserpine) may have an additive effect when given with beta-blocking agents.
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A minimum of 4 and a maximum of 15 clinically typical, discrete, (Grade 1 or 2, see table 2 for definition), target actinic keratosis lesions were identified.
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Periodic monitoring of liver function in patients receiving verapamil is therefore prudent.

Cardiac dysrrhythmias of GradeВ 3 or greater were reported in 7В (3%)В patients treated with Gemzar pluscisplatin compared to oneВ (<1%) GradeВ 3 dysrrhythmia reported with cisplatin therapy.
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Adverse experience information is available from more than 14 years of accumulated marketing experience with other formulations of metolazone for which reliable quantitative information is lacking and from controlled clinical trials with MYKROX from which incidences can be calculated.
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Coauthor(s):Kathryn L Hale, MS, PA-C, Medical Writer, eMedicine.