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Author Topic: AFFiRiS GmbH: Milestone Reached In Clinical Trial Of Alzheimer's Vaccine  (Read 9202 times)
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« Reply #360 on: July 07, 2010, 01:31:47 PM »

The way the radiation therapy is given depends on the type and stage of the cancer being treated.
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After intravenous administration of 15 to 275 mg/m2 doses of paclitaxel as 1, 6, or 24 hour infusions, mean values for cumulative urinary recovery of unchanged drug ranged from 1.3% to 12.6% of the dose, indicating extensive non-renal clearance.
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HydergineВ® (ergoloid mesylates) preparations have not been found to produce serious side effects.
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Anterior uveitis associated with ankylosing spondylitis may occur in one eye or both eyes and tends to be recurrent.
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Hydrochlorothiazide is a thiazide diuretic.

A patient who survives the acute phase and is asymptomatic should be closely observed for at least six hours.
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Orbital blowout fractures are cracking or breaks of the facial bones surrounding the eye.
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Recent technical improvements in heart-lung machines are helping to reduce the risk of blood clots forming.
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« Reply #361 on: July 07, 2010, 09:51:34 PM »

Hypercalcemia cannot be prevented, but early detection of the condition allows for normalization of calcium levels and leads to an early medical evaluation to determine the cause.
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Very conservative estimates put the worldwide maternal death toll at 1,650 women daily.
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Additional cardiovascular AEs were seen at the 90 and 210 mg/m2 daily dose levels.
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The copper prevents sperm from making their way through the uterus into the tubes and prevents fertilization.

Instances of irritability, hostility, and intrusive thoughts have been reported during discontinuation of alprazolam in patients with posttraumatic stress disorder.
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Between 7 and 10 percent of patients with skin rash have shown eosinophilia and/or positive ANA titers.
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« Reply #362 on: July 08, 2010, 06:06:54 AM »

Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older.
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Dosage adjustments for renal impairment are not routinely necessary (see Liver Disease and Renal Disease under CLINICAL PHARMACOLOGY, and Use in Patients With Concomitant Illness under PRECAUTIONS).
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If the film in a camera is faulty, the resulting picture will be blurry.

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Acute alcohol intoxication may increase the anticonvulsant effect due to decreased metabolic breakdown.
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Remove the system if it is not positioned completely within the uterus.
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« Reply #363 on: July 08, 2010, 02:41:24 PM »

The doctor should check for another cause of bleeding if the patient does not respond to hormonal treatment.
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An identical twin has a threefold to tenfold greater risk of getting lupus than a nonidentical twin.
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Patients should carefully read and follow the external insulin pump manufacturer’s instructions and the Patient Information leaflet before using Humalog.
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The Interstitial Cystitis Clinical Research Network (ICCRN) is a product of two NIDDK programs: the Interstitial Cystitis Database (ICDB) Study and the Interstitial Cystitis Clinical Trials Group (ICCTG).
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Medications are most effective when taken in anticipation of the involuntary motion; they are less effective for symptom relief after the motion has begun.

The 1-minute wait between individual doses in the dose-titration recommended for general clinical populations may be too short for high-risk patients.
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About half of outbreals were foodborne, 14% person-to-person, 6% recreational water, 3% animal contact, 3% drinking water, and about 20% unknown route of transmission.
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For example, using an oil-based lubricant with a latex condom will cause it to fall apart.
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« Reply #364 on: July 08, 2010, 11:07:34 PM »

Significant radioactivity (parent plus metabolites) detected in the milk of lactating rats suggests a potential for exposure to nursing infants.
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Triaging of patients by EMSS that includes the routing of patients past closer hospitals in favor of direct transport to recognized stroke centers may have financial or competitive impacts on hospitals.
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A common approach is to complete the noninvasive portions of the evaluation first, avoiding angiography when there is an obvious and adequate explanation for a hemorrhage.
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The chronic inflammatory myopathies can’t be cured in most adults but many of the symptoms can be treated.
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The most typical laboratory finding in people with polymyalgia rheumatica is an elevated erythrocyte sedimentation rate, commonly referred to as the sed rate.

Symptoms of the former range from rhinorrhea and shortness of breath to severe asthma and the latter may consist of urticaria, edema, rash, or angioedema (giant hives).
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Information on concurrent usage of atenolol and aspirin is limited.
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« Reply #365 on: July 09, 2010, 07:40:40 AM »

Treatment consists of surgery, radiation, chemotherapy, and some other approaches under investigation.
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Catheterization of the ureters may be indicated for complete renal blockage by crystals.
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In dogs treated with an oral dose of 1 mg/kg/day (approximately 5 times the human 35 mg/week dose based on surface area, mg/m2), risedronate caused a delay in fracture healing of the radius.
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The capacity of elderly patients (age range: 68 to 89 years) to eliminate valproate has been shown to be reduced compared to younger adults (age range: 22 to 26). Intrinsic clearance is reduced by 39%; the free fraction is increased by 44%. Accordingly, the initial dosage should be reduced in the elderly.
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People with PTSD may be supported while recalling their traumatic event in a safe setting, reducing the fear it produces.
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Distribution Once theophylline enters the systemic circulation, about 40% is bound to plasma protein, primarily albumin.
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« Reply #366 on: July 09, 2010, 04:24:46 PM »

In clinical trials with cancer patients, safety and efficacy was similar in patients over 65 years of age and those under 65 years of age; there was an insufficient number of patients over 75 years of age to permit conclusions in that age-group.
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For those with inflammatory bowel disease, the goal becomes symptom control instead of disease cure, since symptoms can occur over the course of a lifetime.
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IN THIS ARTICLEWhat is acromegaly?What is a hormone?What causes acromegaly?What is the pituitary gland?How does a tumor in the pituitary gland cause abnormal growth elsewhere?How common is acromegaly?How do I know if I have acromegaly?What are other symptoms of acromegaly?Why does acromegaly cause vision loss and headache?What is gigantism?What are the complications of acromegaly?Is acromegaly a fatal disease?How is acromegaly diagnosed?What treatments are available for acromegaly?Other questions about acromegalyWhere Can I Go For More Information?Web LinksSynonyms and KeywordsAuthors and EditorsWhat is a hormone?Hormones are natural chemicals made by various organs.

Having a BRCA mutation also predisposes a woman to developing breast cancer at an early age.
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Type I citrullinemia is the most common form of the disorder, affecting about 1 in 57,000 people worldwide.
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« Reply #367 on: July 10, 2010, 12:37:00 AM »

There are two types of radiation therapy.
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Controlled absorption of diltiazem begins within 1 hour, with maximum plasma concentrations being achieved 4 to 6 hours after administration.
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Benign prostatic hyperplasia (BPH) results from enlargement of the prostate, which occurs commonly as men age.
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These approaches sometimes work better when combined with drug treatment for depression, mood stabilization, or psychosis.
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In addition, the serotonin-norepinephrine reuptake inhibitors (SNRIs like venlafaxin (Effexor)) elevate serotonin levels and carry a similar risk when administered with frovatriptan.

In general, they are not as effective as the beta-agonists in treating asthma.
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Human studies for up to one year have not detected any clinically significant effects on the endocrine system.
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Special arteries, called coronary arteries, bring blood to the heart.
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« Reply #368 on: July 10, 2010, 09:05:54 AM »

Patients with spasticity due to traumatic brain injury should wait at least one year after the injury before consideration of long term intrathecal baclofen therapy.
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Bulimia can cause a number of serious medical conditions that could require urgent treatment.
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The relative risk of toxicity is increased with higher trough concentrations.
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Peripheral edema was generally mild, but it was age and dose related and resulted in discontinuation of therapy in about 3% of the enrolled patients.
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Protein binding was constant over the concentration range (1-100 nmol/L) achieved with, and exceeding, recommended doses of PULMICORT FLEXHALER.
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These medications relieve pain extremely well and although they may cause sedation (sleepiness), they allow muscles to relax and help a great deal while the doctor works on the elbow.

Because of the delay inherent in getting an ambulance to the cardiac arrest victim within those critical first few minutes, many people continued to die from ventricular fibrillation.
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The bruises result from a reaction and response to Candida in blood vessels.
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These doses are from approximately 2.1 to 4.2 times the maximum recommended total daily dose of promethazine for a 50-kg subject, depending upon the indication for which the drug is prescribed.
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« Reply #369 on: July 10, 2010, 05:36:21 PM »

The safety profile of SINGULAIR in the 8-week, double-blind, pediatric efficacy trial was generally similar to the adult safety profile.
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Most of these new cases could have been reduced in severity if there had been vigilant treatment and monitoring of the eyes.
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An effective splint helps to prevent further injury and to provide substantial pain relief.
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Metabolic and Nutritional—Frequent: weight gain; Infrequent: dehydration, generalized edema, gout, hypercholesteremia, hyperlipemia, hypokalemia, peripheral edema; Rare: alcohol intolerance, alkaline phosphatase increased, BUN increased, creatine phosphokinase increased, hyperkalemia, hyperuricemia, hypocalcemia, iron deficiency anemia, SGPT increased.
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There is mental slowing, profound lethargy, and ultimately coma.
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There were no significant differences in plasma protein binding observed between the two groups.

Over-the-counter medicines like ibuprofen (Advil) or acetaminophen (Tylenol) may be used to reduce fever or aches.
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These adverse effects do not appear to have resulted from intrauterine ACE-inhibitor exposure that has been limited to the first trimester.
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You need to call your doctor if you experience fever, excessive bleeding, urinary retention, or testicular pain.
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« Reply #370 on: July 11, 2010, 01:58:56 AM »

If, during the cardiovascular evaluation, the patient’s medical history or electrocardiographic investigations reveal findings indicative of or consistent with coronary artery vasospasm or myocardial ischemia, sumatriptan should not be administered (see CONTRAINDICATIONS).
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If the film in a camera is faulty, the resulting picture will be blurry.
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And they saw government resources that seemed primed to fund some of medicine's most coveted goals evaporate.
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Pregnancy Category C. Animal reproduction studies have not been conducted with INVERSINE[#footnote-1 1]. It is not known whether INVERSINE[#footnote-1 1] can cause fetal harm when given to a pregnant woman or can affect reproductive capacity.
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Impaired renal function at any time requires close monitoring, and frequent dosage adjustment may be indicated.
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Physical examination for hip pain will focus on the hip, leg, and back, however, the rest of the body will not be ignored, looking for associated findings that may help explain the patient's complaints.

Scientists are looking at what role genes play in the development of these disorders.
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Most surgeons do allow you to brush your teeth and take medicine.
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A newborn with anophthalmia or microphthalmia will need to visit several eye care professionals, including those who specialize in pediatrics, vitreoretinal disease, orbital and oculoplastic surgery, ophthalmic genetics, and prosthetic devices for the eye.
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« Reply #371 on: July 11, 2010, 10:13:22 AM »

This nerve, as its name suggests, is the primary motornerve of the extraocular muscles.
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They help you see that your situation is not unique and not hopeless, and that gives you power.
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The prognosis is dependent upon the underlying disorder.
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Giardiasis may lead to lactose intolerance during the infection and up to several weeks after treatment.
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Vaccines have been implicated in Kawasaki disease.
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On Sunday the patient should throw out the rest of the pack and start a new pack that same day.

The reason some people develop GERD is still unclear.
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The section on the right shows a section from a monkey 7 years after receiving ecstasy.
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The first, ulcerative colitis, is thought to be an autoimmune illness in which the body's immune system attacks the colon and causes inflammation.
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« Reply #372 on: July 11, 2010, 06:57:11 PM »

The binding is concentration independent.
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Deep space infections: The deep space infection that arises in the web space of the fingers is also called a collar button abscess.
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The effectiveness of Anafranil for the treatment of OCD was demonstrated in multicenter, placebo-controlled, parallel-group studies, including two 10-week studies in adults and one 8-week study in children and adolescents 10 to 17 years of age.
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Insulin stimulates potassium movement into the cells, possibly leading to hypokalemia that left untreated may cause respiratory paralysis, ventricular arrhythmia, and death.
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The treatment of leg pain depends upon the diagnosis.
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Hypersensitivity to any of the components of Trivora (levonorgestrel and ethinyl estradiol tablets–triphasic regimen).

The suppressive therapy should be continued for eight weeks after leaving the endemic area.
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Internal radiation therapy uses a radioactive substance sealed in needles, seeds, wires, or catheters that are placed directly into or near the cancer.
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These reactions are listed in an approximate decreasing order of occurrence: dryness, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, striae, and miliaria.
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« Reply #373 on: July 12, 2010, 02:58:38 AM »

As with other antibiotic preparations, use of this product may result in overgrowth of nonsusceptible organisms, including fungi.
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Patients who may be at increase risk for substance abuse include those with a personal or family history of substance abuse (including drug or alcohol abuse) or mental illness.
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Single-dose sirolimus did not affect steady-state 12-hour plasma ketoconazole concentrations.
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Amphetamines may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly.
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There is a distinction between patients who develop ascites because of liver disease and cirrhosis, and those who develop it because of inflammation of the peritoneum because of cancer.

Patients should always carry a quick source of sugar, such as hard candy or glucose tablets.
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How leukotrienes work: Leukotrienes are chemical substances that promote the inflammatory response seen during exposure to allergens.
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More than that may be excessive.
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« Reply #374 on: July 12, 2010, 11:39:15 AM »

Premature Pubarche is isolated development of pubic hair without other signs of puberty.
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The pharyngeal gut and stomodeum both contribute to development of the mouth.
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The retinoids may be taken by mouth or applied to the skin.
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Angioedema of the face, extremities, lips, tongue, glottis, and larynx has been reported in patients treated with angiotensin-converting enzyme inhibitors.
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Histamine is an example of a mediator.

However, at 25 times the human dose, fetal malformations were not observed; the relevance of these findings to humans is uncertain.
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Fentanyl plasma protein binding capacity decreases with increasing ionization of the drug.
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The person's walk (gait) and coordination will be tested.
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