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Elderly patients and patients with hepatic insufficiency have decreased clearance of amlodipine with a resulting increase in AUC of approximately 40–60%, and a lower initial dose may be required.
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Initiation of the publicly funded Human Genome Project was the culmination of several years of work beginning in the 1980s. The research funding was started in 1990 by the U.S. Department of Energy and the U.S. National Institutes of Health, and was expected to take more than 15 years.
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When standard methods to treat kidney pain do not work, then removing the fluid in the kidney cysts may be done.
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Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum.
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The present data indicate that intentional hemodilution, with or without venesection in clinical practice, does not reduce case fatality or improve functional outcome in survivors.
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Clinical symptoms of hyperammonemic encephalopathy often include acute alterations in level of consciousness and/or cognitive function with lethargy or vomiting.
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ITBS can also occur at the hip joint, where the IT band connects to the hip.
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Small asymptomatic petechiae are much less important than hematomas, which can be associated with neurological decline.
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Just as the selection of the most appropriate treatment depends on the cause of the tremor and should be done by a physician who is an expert in the diagnosis and treatment of these conditions, the same principle applies for the follow-up.
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The popular oversized racquets can put too much strain on the arm and increase the risk of injury.

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This has been observed with Benedict's and Fehling's solutions but not with the glucose enzymatic test.
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Obstet Gynecol.
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These two smaller molecules are more easily absorbed by the body and used for metabolism.
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IN THIS ARTICLERectal Bleeding OverviewRectal Bleeding CausesRectal Bleeding SymptomsWhen to Seek Medical CareExams and TestsRectal Bleeding TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upOutlookSynonyms and KeywordsAuthors and EditorsRectal Bleeding SymptomsRectal painBright red blood present in or on the stoolChange in stool color to black, red, or maroonStool test positive for occult blood loss (blood may present, but you cannot see it)ConfusionDizziness or lightheadednessFainting1234567891011« Previous PageGlossaryNext Page »Next: When to Seek Medical Care » Printer-Friendly Format |  Email to a Friend Privacy Policy GI Disorders Get the latest treatment options.
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CYP2C19 isoenzyme exhibits polymorphism in the metabolism of esomeprazole, since some 3% of Caucasians and 15-20% of Asians lack CYP2C19 and are termed Poor Metabolizers.
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Researchers are studying whether using coenzyme Q10 along with conventional therapies has any effect, good or bad, on the way these conventional therapies work in the body.
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Warning signs of imbalance are: dryness of mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pains or cramps, muscle fatigue, hypotension, oliguria, tachycardia, and gastrointestinal disturbances such as nausea and vomiting.
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However, the risk and severity of many side effects is reduced if precautions are taken.
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The steady-state pharmacokinetics of digoxin were not altered by concomitant administration of multiple doses of famciclovir (500 mg t.i.d.). No clinically significant effect on the pharmacokinetics of zidovudine, its metabolite zidovudine glucuronide or emtricitabine was observed following a single oral dose of 500-mg famciclovirВ co-administered with zidovudine or emtricitabine.
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Phase 2 Open Label Studies: Two studies were conducted in 53 patients previously treated with a maximum of one prior chemotherapeutic regimen.
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The anserine bursae are located on the inner side of the knee about 2 inches below the joint.

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IN THIS ARTICLEPlague IntroductionPlague CausesPlague Signs and SymptomsPhysician DiagnosisPlague TreatmentPrognosisPreventionFor More InformationWeb LinksMultimediaSynonyms and KeywordsReferencesAuthors and EditorsPreventionA previously used plague vaccine is no longer manufactured.
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There was no significant difference in the pharmacodynamic effect of warfarin administered alone and warfarin administered with etodolac as measured by prothrombin time.
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Protect the patient’s airway, establish an intravenous line and initiate gastric decontamination.
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Similarly, patients who experience other symptoms or signs suggestive of decreased arterial flow, such as ischemic bowel syndrome or Raynaud syndrome following naratriptan administration should be evaluated for atherosclerosis or predisposition to vasospasm (see CONTRAINDICATIONS and WARNINGS).
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Parkinson's disease causes a 4- to 6-Hz resting tremor in the arms and legs that responds to the use of anticholinergics and a combination of carbidopa and levodopa.
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The outer ear may be red, and in severe cases the ear canal may be swollen shut.
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Women with migraine (particularly migraine with aura) who take combination oral contraceptives may be at an increased risk of stroke.
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A bone mineral density test can also monitor the effects of treatment if the tests are performed a year or more apart and may help determine the rate of bone loss.
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Telbivudine is a prescription drug used for the treatment of chronic hepatitis B in adults.

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Pulmonary edema is due to left heart failure, in which pressure backs up into the blood vessels of the lungs, but some patients also have associated right heart failure.
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SYMBYAX has not been evaluated or used to any appreciable extent in patients with a recent history of myocardial infarction or unstable heart disease.
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Most spontaneous reports of fatal GI events are in elderly or debilitated patients and therefore, special care should be taken in treating this population.
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Mean change from baseline in FEV1 in the PULMICORT FLEXHALER 180 mcg, 2 inhalations twice-daily group was 0.28 liters, as compared to 0.10 liters in the placebo group (p<0.001). Secondary endpoints of morning and evening peak expiratory flow rate, daytime asthma symptom severity, nighttime asthma symptom severity, daily rescue medication use, and the percentage of patients who met predefined asthma related withdrawal criteria showed differences from baseline favoring PULMICORT FLEXHALER over placebo.
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A variety of outpatient heart rate monitoring devices can be worn by the patient to try to capture and record abnormal beats.
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Tooth Squeeze OverviewTooth squeeze occurs during a scuba dive ascent when air is trapped in a filling or cavity.
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Still others, such as growing children, need extra nutritional support.
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This outbreak occurred in 1979, in soldiers at Fort Dix, New Jersey.
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At first very short, the esophagus lengthens both prenatally and postnatally.
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Metoclopramide elevates prolactin levels and the elevation persists during chronic administration.

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The NIDDK is part of the National Institutes of Health of the U.S. Department of Health and Human Services.
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The neck contains many vital anatomic structures, the most critical being the airway, the spinal cord, and the blood vessels that supply the brain.
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When the heart stops oxygen isn't pumped to the brain.
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There are no data directly comparing the safety and efficacy of b.i.d. versus q.d. dosing.
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A healthy immune system produces proteins called antibodies and specific cells called lymphocytes that help fight and destroy viruses, bacteria, and other foreign substances that invade the body.
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Diuretic agents reduce the renal clearance of lithium and add a high risk of lithium toxicity.
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Go to the closest, most appropriate hospital immediately.
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Other treatments for a specific disease may be started.
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The acute myocardial infarct can be visualized from 24 hours to nine days following onset of symptoms, with maximum localization at 48 to 72 hours.
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Tighten the tourniquet only enough to stop the bleeding.
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Previous PageGlossary Printer-Friendly Format |  Email to a Friend Privacy Policy Women's Health Find out what women really need.
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Choose unsaturated fats when eating fats and oils such as canola, olive, or sunflower oils, soft or liquid margarine, and nuts.

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It rises up into the body and parts a bit to make space for the sperm to swim up and into the uterus.
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Which treatment is best depends on the type and cause of the urinary incontinence.
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Therefore, use of this drug in pregnancy, in nursing mothers, or in women of childbearing potential requires that the potential benefits of the drug be weighed against the potential hazards to mother and child.
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Infusion periods of less than 20В minutes are not recommended because peak serum levels may exceed 12 mcg/mL (see WARNINGS box).
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IN THIS ARTICLEAnkle Sprain OverviewAnkle Sprain CausesAnkle Sprain SymptomsWhen to Seek Medical CareExams and TestsAnkle Sprain TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upPreventionOutlookMultimediaSynonyms and KeywordsAuthors and EditorsMultimediaMedia file 1: Medial and lateral malleoli, the "bumps" on either side of the ankle.
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During the night, the patient may take 4 mg of loperamide every 4 hours.
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Editors: Ivette Motola, MD, Staff Physician, Department of Emergency Medicine, Harvard Medical School; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; James Kimo Takayesu, MD, Staff Physician, Department of Emergency Medicine, Brigham and Women's Hospital/Massachusetts General Hospital.
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As treatment progresses, other professionals often help.
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Rarer forms occur because of a defect in the thirst mechanism (dipsogenic DI) or during pregnancy (gestational DI).
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Any delay in emergency medical care greatly increases the risk to a person having a severe allergic reaction.
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Insulin requirements may be decreased in the presence of drugs that increase insulin sensitivity or have hypoglycemic activity, such as oral antidiabetic agents, salicylates, sulfa antibiotics, certain antidepressants (monoamine oxidase inhibitors), angiotensin-converting-enzyme inhibitors, angiotensin II receptor blocking agents, beta-adrenergic blockers, inhibitors of pancreatic function (e.g., octreotide), and alcohol.
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A randomized trial testing nimodipine found that unfavorable outcomes among patients treated with the medication were associated with lowering of the blood pressure.

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Since the function of the blood is to carry oxygen and other nutrients, this poor circulation causes decreased oxygen delivery to tissues in different parts of the body and subsequent damage to those tissues.
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It can also detect cysts in the kidneys of a fetus, but large cyst growth this early in life is uncommon in autosomal dominant PCKD.
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Fundus photographs, which are pictures of your optic disc (the front surface of your optic nerve), are sometimes taken for future reference and comparison.
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In pediatric patients aged 2 to 5 years who received 5 mg of cetirizine, the mean Cmax was 660 ng/mL.
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The genetic causes of several other types of malignant hyperthermia (MSH2, MSH4, and MSH6) are still under study.
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The time needed for the concentration of gefitinib in the blood to be reduced by half, the half-life, is 31–41 hours.
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It acts like a spacer, or shim, to separate the worn-out knee surfaces.
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If appropriate, angiotensin converting enzyme (ACE) inhibitors and beta blocker medications may be used to allow the heart to beat more efficiently, potentially increasing cardiac output.
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Because the potential for HIV cross-resistance among protease inhibitors has not been fully explored, it is unknown what effect amprenavir therapy will have on the activity of subsequently administered protease inhibitors.
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The relative risk of toxicity; for example, nephrotoxicity and post-transplant diabetes mellitus, is increased with higher trough concentrations.
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Dopamine produces nausea and vomiting by stimulation of the medullary chemoreceptor trigger zone (CTZ), and metoclopramide blocks stimulation of the CTZ by agents like l-dopa or apomorphine which are known to increase dopamine levels or to possess dopamine-like effects.
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Diuretics have been used at the following dosages when starting therapy with LONITEN: hydrochlorothiazide (50 mg, b.i.d.) or other thiazides at equieffective dosage; chlorthalidone (50 to 100 mg, once daily); furosemide (40 mg, b.i.d.). If excessive salt and water retention results in a weight gain of more than 5 pounds, diuretic therapy should be changed to furosemide; if the patient is already taking furosemide, dosage should be increased in accordance with the patient's requirements.
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If an autopsy is not ordered by the coroner or medical examiner, the relatives of the deceased must give consent for an autopsy to be performed.
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Dosage in children is proportional to adults, based on weight.
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IN THIS ARTICLEEndocrine System IntroductionHypothalamusPituitary GlandThyroid GlandParathyroid GlandsAdrenal GlandsPineal BodyReproductive GlandsPancreasFor More InformationWeb LinksPicturesSynonyms and KeywordsAuthors and EditorsAdrenal GlandsThe adrenal glands are triangular-shaped glands located on top of each kidney.
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If your work involves chemicals, make sure you are protected.
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Previously, scientists discovered the three-dimensional molecular structure of the anthrax protective antigen protein bound to one of the receptors (CMG2) it uses to enter cells.
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Evidence of previous heart attack or ventricular hypertrophy (heart muscle thickening) can be noted on the EKG.
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Collapsed lung can happen after only a slight blow to the chest, or even while at rest without a known cause.
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Additional laboratory abnormalities observed in clinical studies of EPIVIR were thrombocytopenia and elevated levels of bilirubin, amylase, and lipase.
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People affected by Werner syndrome usually live into their late forties or early fifties.
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Throw away the full container according to directions provided by your doctor.
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However, mutations (changes in the genetic material of the virus) often occur in the virus, and it is possible that some mutations could create a more contagious virus that could cause a worldwide pandemic of flu among humans.
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These conditions are characterized by difficulty breathing and shortness of breath.
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Depression affects people of all races, incomes, and ages, but it is 3-5 times more common in elderly people than in young people.
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Calcitonin acts primarily on bone, but direct renal effects and actions on the gastrointestinal tract are also recognized.

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Consultation with other medical specialists may be done if indicated.
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Because unenhanced scanning may provide adequate diagnostic information in the individual patient, the decision to employ contrast enhancement, which may be associated with risk and increased radiation exposure, should be based upon a careful evaluation of clinical, other radiological, and unenhanced CT findings.
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Researchers believe that these chromosomal changes are related to the overall instability of an affected person's genetic information.
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The goal is for the provider to understand the frequency, duration, and context of the pain in relationship to the daily activities of the patient.
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More research is needed on these topics before any conclusions can be drawn.
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Intense itching is again the prominent complaint.
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Clopidogrel bisulfate prolongs the bleeding time and therefore should be used with caution in patients who may be at risk of increased bleeding from trauma, surgery, or other pathological conditions (particularly gastrointestinal and intraocular).
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If a narrowing of a renal artery is discovered, sometimes a balloon dilatation, followed by placement of a metal stent, is done in the invasive vascular laboratory.

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If digoxin or colchicine are used concurrently with cyclosporine, close clinical observation is required in order to enable early detection of toxic manifestations of digoxin or colchicine, followed by reduction of dosage and its withdrawal.
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Women, especially after 85 years of age, are more likely than men to be affected, possibly due to decreased estrogen levels experienced after menopause.
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The signs and symptoms of NMH are similar to those of orthostatic hypotension.
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However, oxygen pre-breathing has to be continued without interruption with in-flight, pure oxygen to provide effective protection against altitude DCS.
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This treatment is a method of giving high doses of chemotherapy and radiation therapy and replacing blood-forming cells destroyed by the cancer treatment.
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A report of “Intermediate” indicates that the result should be considered equivocal, and, if the microorganism is not fully susceptible to alternative, clinically feasible drugs, the test should be repeated.

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Once symptoms of peripheral neuropathy go away completely, you and your doctor should decide if starting VIDEX is right for you.
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Complete blood counts including platelets should be monitored regularly (see ADVERSE REACTIONS and DOSAGE AND ADMINISTRATION).
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Sexual Dysfunction - The rate of sexual dysfunction in male patients with OCD who were treated with Anafranil in the premarketing experience was markedly increased compared with placebo controls (i.e., 42% experienced ejaculatory failure and 20% experienced impotence, compared with 2.0% and 2.6%, respectively, in the placebo group).

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