Repligen Receives Orphan Drug Designation From The FDA For RG1068 For MRI Imaging Of The Pancreas

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Made up of proteins and sugars, strands of proteoglycans interweave with collagens and form a mesh-like tissue.
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You and your child should discuss all treatment choices with your healthcare provider, not just the use of antidepressants.
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Confusion may also arise from the fact ADD/ADHD symptoms, vary with each individual, and some mimic those of other causes.
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Fluorouracil also causes chromosomal abnormalities in the mouse micronucleus test in vivo.
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Deaths associated with the administration of sulfasalazine have been reported from hypersensitivity reactions, agranulocytosis, aplastic anemia, other blood dyscrasias, renal and liver damage, irreversible neuromuscular and central nervous system changes, and fibrosing alveolitis.
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Shorter acting muscle relaxants than NUROMAX may be more suitable for these patients.
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Pessary therapy is an integral part of the management of later stage POP.

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Supportive therapy for control of fever, headaches and muscle pain are usually sufficient to keep people comfortable until the illness has resolved.
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Throughout the pancreas are clusters of cells called the islets of Langerhans.
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The vial contents are under a negative pressure to minimize aerosol formation during reconstitution; therefore, particular care should be taken when the needle is inserted.
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In: Garattini S, Berendes H, eds.
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Therefore, small number of individual platelets may be seen under the microscope, and this can be confused with true thrombocytopenia.
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Such an observation should be corroborated with appropriate diagnostic patch testing.
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Angioplasty can prevent premature death due to CAD.

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Ultrasound can detect clots or blockage of blood flow, especially in larger, more proximal (upper leg) veins.
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One of the easiest tests to perform is pulse oximetry, sometimes called "pulse ox.
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Some conditions require hospitalization, surgical repair, physical therapy, or other rehabilitative measures.
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In this case, the phenotype appears the same in both the heterozygous and homozygous states.
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Evidence gathered in preclinical studies suggests that mirtazapine enhances central noradrenergic and serotonergic activity.
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It frequently affects the piriformis muscle; much of this pain can be relieved through yoga.
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Nasal adverse events were most common with 70% mild, 25% moderate, and 5% severe in nature (placebo rates were 71% mild, 27% moderate, and 2% severe).
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Gefitinib undergoes extensive metabolism in the liver, predominantly by the CYP3A4 enzyme.
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Diltiazem hydrochloride prolongs AV node refractory periods without significantly prolonging sinus node recovery time, except in patients with sick sinus syndrome.

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Inflammation may be caused by infection from certain sexually transmitted diseases (STDs) or by injury to the cervix from a foreign object inserted in the vagina, from birth control devices such as the cervical cap or a diaphragm, or by cancer.
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There are also many other places to get materials and information about cancer treatment and services.
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It may be ordered if an infection or anemia is suspected.
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The other products of amoxicillin and clavulanate potassium do not contain phenylalanine and can be used by phenylketonurics.
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It is a relatively hydrophilic compound which is very soluble in water and freely soluble in alcohol.
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Overall, papillary thyroid cancer is associated with a high survival rate.
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After 4 weeks, effects on heart rate, plasma glucose, and plasma potassium were generally diminished compared with day 1 in all active treatment groups.
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People who are at low risk for cancer, or even have no symptoms, should schedule a colonoscopy every 3-5 years after age 50 years.
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Even though she doesn’t have the condition, she can pass the gene on to her children.

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The most common age of onset is seven years of age.
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Amphetamines may impair the ability of the patient to engage in potentially hazardous activities such as operating machinery or driving a motor vehicle; the patient should therefore be cautioned accordingly.
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Instances of withdrawal symptoms in the neonate have been reported following usage during pregnancy.
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The cause of this damage is often unknown.
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CTCL is a cancer of the T cells, which are a type of white blood cell.
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The physician may consider tapering Cymbalta in the thirdВ trimester.
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Tobramycin has appeared in low concentration in the cerebrospinal fluid following parenteral administration, and concentrations are dependent on dose, rate of penetration, and degree of meningeal inflammation.

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An Advisory Committee of the FDA discussed this issue in 1989 and recommended that the benefits of low-dose oral contraceptive use by healthy, non-smoking women over 40 years of age may outweigh the possible risks.
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The scans present evidence that the disorder has a biochemical, rather than an environmental, cause.
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For such a plan to succeed, it must involve long-term changes in the habits of the entire family.
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In most patients, if the source of excess water intake is eliminated, the body's kidneys can correct the sodium abnormalities on its own.
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In 12 healthy volunteers, 0.5, 1, and 1.5 mg doses resulted in complete prolactin inhibition, with a maximum effect within 3 hours in 92% to 100% of subjects after the 1 and 1.5 mg doses compared with 50% of subjects after the 0.5 mg dose.
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NSAIDs, including meloxicam, can cause serious skin adverse events such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal.
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People with COPD, their family members, and their caregivers are warned not to smoke when supplemental oxygen is in use.

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In addition to patient status and health history, this information should encompass clinical process data, as well as results tracking, which includes outcomes data, guideline compliance rates, and the reasons for variance (departures) from the guideline recommendations.
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There have been reported instances of psychological and physical dependence and tolerance in patients abusing NUBAIN.
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Exchange transfusion or dialysis may be required as means of reversing hypotension and/or substituting for disordered renal function.
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Before use, examine the product to assure that all solids are redissolved.
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To prevent hypokalemia and metabolic alkalosis, an aldosterone antagonist or potassium-sparing drug should be used concomitantly with torsemide.
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It may be bent upward or at strange angles.
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The challenges in transporting patients to primary or comprehensive stroke centers include an inadequate number of stroke centers in both urban and rural areas, insufficient specialty physicians in some geographic areas, and a backlog of applications for hospitals to become certified by the Joint Commission on Accreditation of Healthcare Organizations or other appropriate body.
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Pentazocine may cause physical and psychological dependence when taken alone and may have additive CNS depressant properties when taken in combination with alcohol or other CNS depressants.

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In some cases only these stronger cough suppressants can stop a vicious cycle of coughing leading to more irritation of the bronchial tubes, which in turn causes more coughing.
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It is curved upon itself and placed very obliquely, its base projecting forward and forming the prominent sacrovertebral angle when articulated with the last lumbar vertebra; its central part is projected backward, so as to give increased capacity to the pelvic cavity.
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In severe cases, affected infants experience profoundly weak muscle tone (hypotonia) and serious or life-threatening breathing problems.
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No long-term studies in animals have been performed to evaluate the carcinogenic potential of eptifibatide.
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F31.4      Bipolar affective disorder, current episode severe depression without psychotic symptomsThe patient is currently depressed, as in severe depressive episode without psychotic symptoms (F32.2), and has had at least one authenticated hypomanic, manic, or mixed affective episode in the past.
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When the cornea becomes cloudy, light cannot penetrate the eye to reach the light-sensitive retina.
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Even in its later stages, the signs of the disease are similar to those of other conditions, so those conditions must be ruled out before a diagnosis can be made.
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Corticosteroid eye drops may increase pressure in the eye; therefore, people with cataracts or glaucoma must use them with caution.

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Hydromorphone is extensively metabolized via glucuronidation in the liver, with greater than 95% of the dose metabolized to hydromorphone-3-glucuronide along with minor amounts of 6-hydroxy reduction metabolites.
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The development of mucosal alterations or transient nasal conditions have been reported in up to 9% of patients who received a calcitonin-salmon nasal spray and in up to 12% of patients who received placebo nasal spray in studies in postmenopausal women.
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IN THIS ARTICLECyanide Poisoning OverviewCyanide Poisoning CausesCyanide Poisoning SymptomsWhen to Seek Medical CareExams and TestsCyanide Poisoning TreatmentSelf-Care at HomeNext StepsFollow-upPreventionOutlookSynonyms and KeywordsAuthors and EditorsCyanide Poisoning TreatmentDepending on how sick the patient is, treatment will vary.
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Inc; William D James, MD, Program Director, Vice-Chair, Paul R Gross Professor, Department of Dermatology, University of Pennsylvania School of Medicine.
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Concomitant use of fluoxetine and pimozide is contraindicated (see CONTRAINDICATIONS).
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In the latter category, one of the most important is the use of antibiotics.

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Abnormal curving of the spine, called scoliosis, lordosis, or kyphosis, can occur.
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Although all of these disorders include inflammation of the blood vessels, most differ from each other in terms of what populations of people they affect and which organs are involved.
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Amounts of vitamin B12 that are recommended by the Food and Nutrition Board, National Academy of Science-National Research Council for pregnant women (4 mcg daily) should be consumed during pregnancy.
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The most useful microbiologic test is the standard blood culture, which is almost always positive in victims with anthrax throughout their bodies.
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LIORESAL (baclofen USP) given orally has been shown to increase the incidence of omphaloceles (ventral hernias) in fetuses of rats given approximately 13 times on a mg/ kg basis, or 3 times on a mg/m2 basis, the maximum oral dose recommended for human use; this dose also caused reductions in food intake and weight gain in the dams.
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Catheters are thin, flexible tubes used in a procedure called cardiac catheterization.
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In addition, more patients in the Rapamune with cyclosporine group had a pretransplantation history of skin carcinoma.
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He or she may prescribe steroid and antibiotic eyedrops or ointments to be given while you are in the hospital.

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Most often, acute pericarditis is self-limiting and will resolve within a few weeks.
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These bugs usually infest poor-quality dwellings and are most active at night.
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The bcr-abl gene is formed on chromosome 22 where the piece of chromosome 9 attaches.
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The healthcare provider will examine the patient and ask questions about symptoms.
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Surgeons differ in their opinions about when breast reconstruction should be performed.
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Patients at greater risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACE inhibitors, and the elderly.
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The buildup of fluid usually forces the two layers of the pleura apart so they don't rub against each other when breathing.
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About 88% of recipients survive the first year after transplant surgery, and 72% survive for five years.
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Due to the nature and limitations of spontaneous reporting, causality has not been established for the following adverse events received for nalbuphine hydrochloride injection: abdominal pain, pyrexia, depressed level or loss of consciousness, somnolence, tremor, anxiety, pulmonary edema, agitation, seizures, and injection site reactions such as pain, swelling, redness, burning, and hot sensations.

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It is more common in adults who are older than 60 years and is rarely found in people who are younger than 20 years.
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The risk factors for first stroke and the risk factors for cardiovascular disease overlap.
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These publications discuss types of cancer, methods of cancer treatment, coping with cancer, and clinical trials.
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In contrast, ophthalmic timolol significantly decreased these pulmonary functions.
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Today, in addition to traditional uses, people take aloe orally to treat diabetes[4][5] and asthma,[6] and use it topically (externally) for skin conditions like burns, sunburns, psoriasis, eczema, and genital herpes.
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If the specific cause of colitis is not readily apparent, then colonoscopy may be considered.
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This slows the flow of blood and the oxygen blood carries to all parts of the body.
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In some patients with syphilis (especially in the latent or late stages), a lumbar puncture (spinal tap) must be done to check for infection of the nervous system.
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BMI is defined as weight in kilograms divided by height in meters squared (kg/m 2). BMI also can be calculated in pounds and inches.

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Most cases were directly linked to contact with swine through farming or at fairs.
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This means that children who get exercise are more likely to reach a higher peak bone density (maximum strength and solidness), which usually occurs by age 30 years.
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A dysmorphologist is a medical doctor, usually a medical geneticist or pediatrician, who is trained to assess and treat congenital malformations.
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Staff members can provide information about poison prevention and telephone stickers with the telephone number for the national poison control center.
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IN THIS ARTICLEGastroenteritis OverviewGastroenteritis CausesGastroenteritis SymptomsWhen to Seek Medical CareExams and TestsGastroenteritis TreatmentSelf-Care at HomeMedical TreatmentMedicationsNext StepsFollow-upPreventionFor More InformationWeb LinksPicturesSynonyms and KeywordsAuthors and EditorsViewer Comments: Gastroenteritis (Stomach Flu) - Effective TreatmentsExams and TestsGastroenteritis is often self-limiting, and the care is supportive to control symptoms and prevent dehydration.
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Patients selected for further study as the result of a subnormal CORTROSYNв„ў test should be given a 3 or 4 day course of treatment with Repository Corticotropin Injection USP and then retested.
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Various underlying conditions have been described in children with CVST (Table .4,5,6,,31,54,380 Many children have multiple risk factors.
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Most patients in clinical trials found that the optimal dosage range is 0.1 mg to 0.8 mg daily, administered in divided doses.

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Refer to the package insert for lithium preparations before use of such preparations with enalapril maleate and hydrochlorothiazide tablets.
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Fever, chills, and headache are some of the symptoms of infection.
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The incidence of hip fractures increases each decade from the sixth through the ninth for both women and men for all populations.
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Fortunately, the stem cells that continually supply the follicle with new cells do not seem to be targeted.
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Elevated plasma levels of Lp-PLA2 are associated with an increased risk of cardiovascular events, independent of other risk factors.
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The dose in rheumatoid arthritis is 1,000 mg given on week 1 and week 4 of treatment.

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Hyperactivity in an older child can be minimized if the starting dose is one-fourth of the recommended full replacement dose, and the dose is then increased on a weekly basis by an amount equal to one-fourth the full-recommended replacement dose until the full recommended replacement dose is reached.
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Careful monitoring is recommended when using methadone in patients with a history of cardiac conduction disease, those taking medications affecting cardiac conduction, and in other cases where history or physical exam suggest an increased risk of dysrhythmia.
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Studies of 2 pregnant dogs given daily injections of 30 Вµmol Ca-DTPA/kg (approximately half the recommended daily human dose based on BSA) from implantation until parturition showed severe teratogenic effects (especially brain damage).
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Safe sex practices such as condom use can help prevent the spread of sexually-transmitted infections.
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