Repligen Receives Orphan Drug Designation From The FDA For RG1068 For MRI Imaging Of The Pancreas

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It is recommended that telithromycin should be taken with theophylline 1 hour apart to decrease the likelihood of gastrointestinal side effects.
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The ICD monitors your heartbeat.
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Birth Control Barrier Methods IntroductionThe practice of birth control or preventing pregnancy is as old as human existence.
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Metabolic clearance rates may differ among individuals by several-fold, and this may account in part for the wide variation observed in levonorgestrel concentrations among users.
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IN THIS ARTICLELens-Particle Glaucoma OverviewLens-Particle Glaucoma CausesLens-Particle Glaucoma SymptomsWhen to Seek Medical CareQuestions to Ask the DoctorExams and TestsLens-Particle Glaucoma TreatmentSelf-Care at HomeMedical TreatmentMedicationsSurgeryNext StepsFollow-upOutlookSupport Groups and CounselingFor More InformationWeb LinksMultimediaSynonyms and KeywordsAuthors and EditorsAuthors and EditorsAuthor: Brian R Sullivan, MD, Assistant Professor, Department of Ophthalmology, University of Texas Southwestern Medical Center.
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The most common side effect is slight skin irritation where the patch is placed.
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Studies are now underway to confirm the positive effects of using metformin in women with PCOS, and to evaluate the safety of taking the drug throughout pregnancy.
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Estraderm therapy may be given continuously in patients who do not have an intact uterus.
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During that day, the person should not engage in activities that require being awake, such as driving.

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Triptans stimulate serotonin (a chemical needed to transmit various nerve signals to the brain), decrease inflammation, and reverse blood vessel dilation (expansion) around the brain, thereby relieving the migraine or cluster headache symptoms.
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More severe reactions include numbness, tingling, weakness, paralysis, nausea, vomiting, joint aches, headaches, and cough.
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Yet, despite great advances in diagnosing and preventing it, today rabies is almost always deadly in humans who contract it and do not receive treatment.
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Depolarization causes receptor cells to release neurotransmitters that stimulate neurons in sensory neural pathways associated with the cranial nerves.
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Maculopapular rash and urticaria have been observed during drug therapy.
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Bisphosphonates can increase bone density and reduce fractures of the hip and spine, but the regimen is complicated, and the adverse effects (i.e. erosive esophagitis) concerning.
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There is a newly licensed vaccine (pneumococcal conjugate vaccine) that appears to be effective in infants for the prevention of pneumococcal infections and is routinely recommended for all children greater than two years of age.
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Children typically have more than one type of seizure.

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Studies have not been conducted to assess the penetration of lomefloxacin into human cerebrospinal fluid.
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Early cardiac toxicity of epirubicin consists mainly of sinus tachycardia and/or ECG abnormalities such as non-specific ST-T wave changes, but tachyarrhythmias, including premature ventricular contractions and ventricular tachycardia, bradycardia, as well as atrioventricular and bundle-branch block have also been reported.
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Relative proportions of PA and N-acetylprocainamide (NAPA) during administration of ProcanbidВ® are similar to those following administration of immediate-release PA or PA HCl extended-release tablets, USP.
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Doctors classify the disorder into 3 types: the Parkinsonian-type includes symptoms of Parkinson's disease such as slow movement, stiff muscles, and tremor; the cerebellar-type, which causes problems with coordination and speech; and the combined-type, which includes symptoms of both parkinsonism and cerebellar failure.
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Manifestations of adrenal suppression in pediatric patients include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation.
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One patient unintentionally took 14 mg/day for 23 days instead of her prescribed 1.4 mg/day dosage.

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Infrequently, signs and symptoms of glucocorticosteroid insufficiency may occur that require supplemental systemic corticosteroids.
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The NCI's LiveHelp® online chat service provides Internet users with the ability to chat online with an Information Specialist.
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Rectal Bleeding OverviewThe rectum is the last portion of the large bowel that ends just before the anus.
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The operation, thalamotomy, can be done by conventional stereotatic surgery or by the use of a Gamma knife (which uses radiation).
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It is the most commonly performed surgical procedure in the treatment of fibroids and is considered a cure.
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Hepatitis A is an acute, self-limiting infection of the liver by the hepatitis A virus (HAV).
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At plasma concentrations between 1 and 10 mg/L, tiludronic acid was approximately 90% bound to human serum protein (mainly albumin).

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Linear dose-proportional pharmacokinetics were demonstrated in a single dose study in which the Cmax and area under the plasma concentration time curve (AUC) of sertraline were proportional to dose over a range of 50 to 200 mg.
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In rare cases, Leigh's disease can begin during late adolescence or early adulthood and progress more slowly.
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It is an intermediate-acting insulin combined with the more rapid onset of action of Regular human insulin.
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In stage 0, abnormal cells are found in the inside lining of the mucosal (innermost) layer of the stomach wall.
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After many years, PCKD can cause the kidneys to fail.

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However, the additional dosage selected must be individualized especially if the anticipated remaining operative time is short.
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The PEPI (Postmenopausal Estrogen-Progestin Intervention) Trial confirmed that regimens using daily doses of 2.5mg MPA are as effective at preventing hyperplasia as those using 13 days of 10 mg MPA.
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In the absence of such data, local epidemiology and susceptibility patterns may contribute to the empiric selection of therapy.
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In response, the brain slows the person's heart rate, which makes the blood pressure drop even further, causing dizziness and other symptoms.
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There have been reports of increased anticoagulant effects when erythromycin and oral anticoagulants were used concomitantly.
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Asthma is a chronic (ongoing, long-term) inflammatory disease that causes difficulty breathing.

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A major feature of LKS is the gradual or sudden loss of the ability to understand and use spoken language.
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A 1 ml ampule (50 mcg/ ml) is available for use in the screening trial.
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Any bottles exhibiting particulate matter or discoloration should not be used.
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This phenomenon is known as the mammalian dive reflex, which is activated when the face and body plunge into ice-cold water, resulting in the slowing of body metabolism as well as diverting blood only to the heart, lungs, and brain.
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Today's leading nutritionists advise against the processing of food where possible, since undiscovered but possibly essential nutrients may be thereby removed, or toxins may be added or produced through processing and high temperature cooking.
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Compress the injured area.
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Intravascular injection of ioversol opacifies those vessels in the path of the flow of the contrast medium, permitting radiographic visualization of the internal structures until significant hemodilution occurs.
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Meperidine should be used with caution in patients with atrial flutter and other supraventricular tachycardias because of a possible vagolytic action which may produce a significant increase in the ventricular response rate.
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The word dyspareunia comes from early Greek language, and its meanings include "difficulty mating" or "badly mated.

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Keratitis is usually diagnosed based on the clinical symptoms of pain and/or redness in the eye along with close examination of the cornea by an eye specialist.
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The disease is caused by a mutation in the gene that controls the production of a myelin protein called proteolipid protein (PLP).
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Mifepristone is rapidly absorbed, with peak circulating levels occurring approximately 90 minutes after ingestion.
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The Shigella bacteria pass from one infected person to the next.
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NCI materials on these and other topics may be ordered online or printed directly from the NCI Publications Locator.
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Treatment should be initiated with a dose of 10 mg/day.
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These clots consume all the clotting factors and platelets in the body, and bleeding begins to occur spontaneously.
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The recommended diluent for reconstitution of Gemzar is 0.9%В Sodium Chloride Injection without preservatives.
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TNF- alpha is a substance that is produced by cells of the body and that has an important role in promoting inflammation.

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Until your baby starts crawling on the floor, a daily bath is not necessary.
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When dihydroergotamine mesylate nasal spray was administered intranasally to female rats during pregnancy and lactation, decreased body weights and impaired reproductive function (decreased mating indices) were observed in the offspring at doses of 0.16 mg/day or greater.
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The usual dose of ofloxacin tablets is 200 mg to 400 mg orally every 12 h as described in the following dosing chart.
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It is unfortunately too frequent that we diagnose spondylitis after a patienthas already undergone a surgical procedure of the low back.
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Last Editorial Review: 8/10/2005 Fats & Your Diet: The Big FAT Truth Get Tips & Recipes from Celebrity Chef Cat Cora Fat Fact or Fat Fiction? 8 Lies Revealed Which Soft Spread is Right for Your Family? Privacy Policy Women's Health Find out what women really need.
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IN THIS ARTICLESwimmer's Ear OverviewSwimmer's Ear CausesSwimmer's Ear SymptomsWhen to Seek Medical CareExams and TestsSwimmer's Ear TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upPreventionOutlookSynonyms and KeywordsAuthors and EditorsAnatomy of an Ear Infection - Slideshow Next StepsFollow-upIn most cases, no additional care or visits to the doctor are necessary.
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Concerns about abuse, addiction, and diversion should not prevent the proper management of pain.
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Inflammation in the eyes can lead to blindness if not diagnosed and controlled early.
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Since only about 5% of oxaprozin dose is excreted unchanged in the urine, the decrease in total body clearance becomes clinically important only in those subjects with highly decreased CrCl.

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Arrhythmogenic right ventricular dysplasia (ARVD) is a rare type of cardiomyopathy.
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Losartan inhibits the pressor effect of angiotensinВ II (as well as angiotensinВ I) infusions.
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Adequate burn care is essential, because skin lesions heal slowly and are prone to infection.
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The use of a peripheral nerve stimulator will permit the most advantageous use of NIMBEX, minimize the possibility of overdosage or underdosage, and assist in the evaluation of recovery.
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If renal function is normal, forced diuresis may aid in the elimination of the barbiturate.
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The temporary threshold shift largely disappears 16 to 48 hours after exposure to loud noise.
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In addition to the adverse events in the table, the following events occurred at a rate of 1% but were at least as frequent in the placebo group: influenza-like symptoms, dyspepsia, myalgia, urinary tract infection, abdominal pain, headache, dizziness, pain, fatigue, coughing, hypertension, chest pain, nausea and peripheral edema.
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Preventative therapy in non-ill patients who have had recent tick bites is not warranted.
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Pharmacokinetics in special populations (for renal, hepatic impairment, and age), obtained after a single dose of 80 mg fexofenadine hydrochloride, were compared to those from healthy volunteers in a separate study of similar design.

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Results of this approach, often referred to as second-line therapy, are rarely curative.
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They may be used alone or to carry drugs, toxins, or radioactive material directly to cancer cells.
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Acute CNS Manifestations.
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Some examples are cimetidine (Tagamet), ranitidine (Zantac), and famotidine (Pepcid).
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Chemotherapy may be taken by pill or put into the body by a needle in a vein or muscle.
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The destruction (ablation) procedures for treatment of cervical dysplasia include carbon dioxide laser photoablation and cryocautery.
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The total dose within 4 hours should not exceed 0.5 mg.
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Red bumps on the skin, swollen lymph nodes, an enlarged liver, spleen, or salivary gland(s), or redness in the eyes are some of the symptoms detected in this exam.
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The status of renal function should be determined by measurement of serum creatinine concentration or calculation of the endogenous creatinine clearance rate.

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In extreme cases of essential tremor, botulinum toxin might be indicated.
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Based on the usual starting doses of glimepiride (1 mg or 2 mg once daily), and pioglitazone 15 mg or 30 mg, DUETACT may be initiated at 30 mg/2 mg once daily, and adjusted after assessing adequacy of therapeutic response.
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Nevertheless, the whole foods approach requires knowledge and purchase of isoflavone-rich sources, caloric reduction to accommodate the isoflavone sources, some culinary creativity, and perhaps a little getting used to.
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Never run the water with baby in the tub because a water temperature change might occur.
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It is unlikely that a person would drink enough green tea to ingest this toxic amount of caffeine.
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It involves injection of small amounts of a liquid chemical using a very fine needle.
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The patient is awake during the procedure, but the doctor numbs the area of the vein.
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This warning is based on the study conducted by the University Group Diabetes Program (UGDP), a long-term prospective clinical trial designed to evaluate the effectiveness of glucose-lowering drugs in preventing or delaying vascular complications in patients with non-insulin-dependent diabetes.

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Some newer machines are designed to allow the patient to lie in a more open space.
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Under the Bethesda System, Pap smear samples that have no cell abnormalities are reported as "negative for intraepithelial lesion or malignancy" (meaning the woman does not have cancer).
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Due to the risk of vascular spasm, exceeding the recommended dosages of Dihydroergotamine Mesylate Injection, USP is to be avoided.
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The following list includes some other MAO inhibitors, dibenzazepine-related entities, and tricyclic antidepressants.
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Gallstones OverviewGallstones (commonly misspelled gall stones) are solid particles that form from bile in the gallbladder.
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Germ cells within the testicles produce immature sperm that travel through a network of tubules (tiny tubes) and larger tubes into the epididymis (a long coiled tube next to the testicles) where the sperm mature and are stored.
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Local anesthesia (such as with injections or lidocaine or application of a topical anesthesia cream) may be indicated for larger skin tags.
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Since the testing often takes 2 to 4 weeks to obtain a final answer, the physician usually does not order these tests.
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If you would like more information, talk to your doctor.

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In normal individuals, the balance of iron concentration in the body is regulated by the amount of iron stored in the body.
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The popularization of modafinil in the mainstream media is of concern to some physicians.
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These findings are consistent with the results of a long-term, randomized, placebo-controlled trial in which glimepiride therapy improved postprandial insulin/C-peptide responses and overall glycemic control without producing clinically meaningful increases in fasting insulin/C-peptide levels.
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Spironolactone and hydrochlorothiazide therapy may cause a transient elevation of BUN.
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Each 100 mL of Lactated Ringer’s Injection, USP contains sodium chloride 600 mg, sodium lactate, anhydrous 310 mg, potassium chloride 30 mg and calcium chloride, dihydrate 20 mg.
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Each genome contains all of the information needed to build and maintain that organism.
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The extremity should be wrapped with a bandage in a style similar to wrapping a sprained ankle.
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The ability to fill and store urine properly requires a functional sphincter muscle to control output of urine from the bladder and a stable detrusor muscle.
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However, since enalapril has been marketed, the following adverse reactions have been reported: Body as a Whole: Anaphylactoid reactions (see [#section-8.1.1.5 WARNINGS: Anaphylactoid Reactions During Membrane Exposure]); Cardiovascular: Cardiac arrest; myocardial infarction or cerebrovascular accident, possibly secondary to excessive hypotension in high risk patients (see [#section-8.1.1.1 WARNINGS: Hypotension]); pulmonary embolism and infarction; pulmonary edema; rhythm disturbances including atrial tachycardia and bradycardia; atrial fibrillation; hypotension; angina pectoris, Raynaud's phenomenon; Digestive: Ileus, pancreatitis, hepatic failure, hepatitis (hepatocellular [proven on rechallenge] or cholestatic jaundice) (see [#section-8.1.1.7 WARNINGS: Hepatic Failure]), melena, anorexia, glossitis, stomatitis, dry mouth; Hematologic: Rare cases of neutropenia, thrombocytopenia and bone marrow depression.