Repligen Receives Orphan Drug Designation From The FDA For RG1068 For MRI Imaging Of The Pancreas

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In rare instances, hemoperfusion may be beneficial in acute refractory cardiovascular instability in patients with acute toxicity.
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Some publications provide information on tests for cancer, cancer causes and prevention, cancer statistics, and NCI research activities.
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Coauthor(s):Jessica B Johnson, Medical Writer, eMedicine.
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Diseases, nutritional status, trauma, surgical procedures, or medications can affect erectile function by altering the nervous, vascular, or hormonal systems.
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Because this growth happens slowly over time, many people, including your primary care doctor, may not notice the change in your appearance.
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L/kg/min) have been observed in elderly subjects when compared to young subjects.
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The recovery period can be several weeks or even months.
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Each g of CordranВ® Ointment (Flurandrenolide Ointment, USP) contains 0.5 mg (1.145 Ојmol; 0.05%) or 0.25 mg (0.57 Ојmol; 0.025%) flurandrenolide in a base composed of white wax, cetyl alcohol, sorbitan sesquioleate, and white petrolatum.
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Injection of Vincristine Sulfate Injection, USP should be accomplished within 1 minute.

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Medicines may be prescribed to manage pain during recovery; lower cholesterol, blood pressure, and the chance of developing blood clots; manage diabetes; or treat depression.
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VISIPAQUE 270 (270 mgI/mL) contains 0.074 mg calcium chloride dihydrate per mL and 1.87 mg sodium chloride per mL, and VISIPAQUE 320 (320 mgI/mL) contains 0.044 mg calcium chloride dihydrate per mL and 1.11 mg sodium chloride per mL, providing for both concentrations a sodium/calcium ratio equivalent to blood.
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An additional option is by deep brain stimulation (DBS) with implanted electrodes.
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Cancer.
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If left uncontrolled, this vicious cycle can lead to kidney failure and damage the heart and blood vessels throughout the body.
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It is indicated for (1) induction of labor in patients with a medical indication for the initiation of labor, such as Rh problems, maternal diabetes, pre-eclampsia at or near term, when delivery is in the best interest of mother and fetus or when membranes are prematurely ruptured and delivery is indicated; (2) stimulation or reinforcement of labor, as in selected cases of uterine inertia; (3) as adjunctive therapy in the management of incomplete or inevitable abortion.
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Once back inside the body, the genetically modified cells can produce the missing immune system component and begin to restore the person’s ability to fight off infections.
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Ultrasound, which passes sound waves through the body to create a picture of the kidneys, is used most often.
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Dehydration is never good for patients taking arthritis medications as it can increase the chances for side effects of the drugs, such as kidney injury.

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Many women experience uterine cramps, also referred to as dysmenorrhea, during this time.
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Penetrating head injuries often require some sort of surgery, usually to remove foreign material or to stop bleeding.
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Apply cool washcloths to the face and neck.
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GRAEF C, ELLENRIEDER B, HECHER K, HACKELOER BJ, HUBER A, BARTMANN P. Long-term neurodevelopmental outcome of 167 children after intrauterine laser treatment for severe twin-twin transfusion syndrome.
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Neither losartan nor its active metabolite can be removed by hemodialysis.
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The rPA vaccines appear to produce an effective immune response in people with intact immune systems.
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Positive test results were obtained in the in vitro CHO Sister Chromatid Exchange (clastogenicity) test, and in the mouse Lymphoma Cell (mutagenicity) assays, using concentrations of hydrochlorothiazide of 43 to 1300 mcg/mL.
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These types of tests generally require at least a few days.

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They account for approximately 8 percent of all tumors inside the skull; one out of every 100,000 individuals per year develops a vestibular schwannoma.
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The prognosis is better for those with single suture involvement and no associated abnormalities.
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Both the Duchenne and Becker forms of muscular dystrophy are associated with a heart condition called dilated cardiomyopathy.
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These bites can cause damaging hand injuries and can be very serious if not properly cared for.
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After the lesion has been present for 2 months, it ceases expanding and after 3 to 6 months begins to heal, leaving a depressed scar.
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If the blood glucose is below your normal fasting glucose, you should consider eating or drinking sugar–containing foods to treat your hypoglycemia.
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If tobramycin is used during pregnancy or if the patient becomes pregnant while taking tobramycin, she should be apprised of the potential hazard to the fetus.
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Notify any and all sexual partners of infection.

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Weight loss has also been shown in many studies to reduce some of the effects of excess testosterone in women with PCOS.
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Oral contraceptives or "birth‑control pills" or "the pill" are used to prevent pregnancy and are more effective than most other nonsurgical methods of birth control.
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Patients should be advised to adhere to dietary guidelines (see [#section-11 DOSAGE AND ADMINISTRATION]). Gastrointestinal events (see [#section-9 ADVERSE REACTIONS]) may increase when XENICAL is taken with a diet high in fat (>30% total daily calories from fat).
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The development of secondary ocular infection (bacterial, fungal and viral) has occurred.
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Streptococcal skin infections are generally treated with penicillin but low levels of resistance have recently been reported.
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Generally, nothing needs to be done if the partner has no signs of developing a genital herpes infection.
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Express concerns with a doctor at the time of examination because this helps to establish a diagnosis.
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The ovaries normally stop making estrogens when a woman is between 45 to 55 years old.
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In U.S. placebo-controlled trials, changes in total cholesterol averaged + 0.8% for bisoprolol fumarate-treated patients, and + 0.7% for placebo.

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Aromatase inhibitors prevent the synthesis of estrogen in postmenopausal women.
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Fecal excretion accounts for 12.5% of the injected dose after 48 hours.
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MS is a disease with a natural tendency to remit spontaneously, for which there is no universally effective treatment.
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Symptoms may present as a form of altered mental status including confusion and loss of memory, or a physical problem such as weakness or numbness of a body part, loss of muscle, uncoordinated movements, seizure, or any combination of the above.
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The resulting fertilised eggs are then implanted directly into the womb, bypassing the fallopian tubes altogether.
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Keep in mind that occasional discomfort in the jaw joint or chewing muscles is common, and is not always a cause for concern.
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Medical events (eg, proarrhythmia, AV block) that occur after the overdosage should be treated with measures appropriate for that condition.
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The excretion of unchanged butabarbital in the urine is negligible.
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The frequency and severity of important adverse events for the phase 3 ovarian carcinoma and breast carcinoma studies are presented above in tabular form by treatment arm.

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An encephalopathic syndrome (characterized by weakness, lethargy, fever, tremulousness and confusion, extrapyramidal symptoms, leukocytosis, elevated serum enzymes, BUN and FBS) has occurred in a few patients treated with lithium plus an antipsychotic.
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As with other insulins, the requirements for NovoLogВ® Mix 70/30 may be reduced in patients with renal impairment.
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The adverse effects of overdosage are life-threatening and affect mainly the pulmonary and cardiovascular system.
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Scratches by infected animals are far less likely to cause infection but are still considered a potential source of rabies transmission.
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Standard medical practices may be used to manage renal insufficiency or hypocalcemia, if signs of these develop.
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Corticosteroids may increase the clearance of chronic high-dose aspirin.
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To understand sudden cardiac arrest, it helps to understand how the heart works.
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If the feared situation or object is easy to avoid, people with specific phobias may not seek help.
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When the estrogen levels begin dropping, some women develop very uncomfortable symptoms, such as feelings of warmth in the face, neck, and chest, or sudden intense episodes of heat and sweating ("hot flashes" or "hot flushes").

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Patient protective wraps: Also known as casualty wraps, these are chemical-protective and biological-protective wraps for casualties in contaminated environments in which personnel are unable to wear battledress overgarments . The top of the garment has a charcoal lining similar to the BDO, while the bottom is constructed of impermeable rubber.
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Changing the diet may not always relieve symptoms of atopic dermatitis.
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When the hernia occurs in the groin, it is called an inguinal hernia.
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Other examples of motion or travel sickness include car sickness and air sickness.
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Research in chinchillas has yielded a potential new therapeutic approach.
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Heart valve disease that develops before birth is called a congenital valve disease.
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Methods and intentions typically termed birth control may be considered a pivotal ingredient to family planning (which aims to help people maintain optimal family sizes and is neutral as to the number of offspring a family wants and can maintain).
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However, there have been reports of increased International Normalized Ratio (INR) and prothrombin time in patients receiving proton pump inhibitors, including lansoprazole, and warfarin concomitantly.

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Past history of medical illness, intentional or unintentional ingestions, prescribed medications, chemical exposure, and infections may provide clues as to why the patient has encephalopathy.
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The doctor may prescribe medicines to help prevent or treat other related heart conditions, such as heart failure, high blood pressure, irregular heartbeats, coronary artery disease (CAD), and life-threatening blood clots.
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IN THIS ARTICLEGastroesophageal Reflux Disease FAQs IntroductionDoes GERD affect my heart?How common is GERD?What causes GERD?What is hiatal hernia?Does GERD have symptoms other than heartburn?Should I see my health care provider if I have these symptoms?Will I have to have tests to see if I have GERD?What is the treatment for GERD?How do antacids work?What are my options if these treatments don't work?When is surgery needed for GERD?How can I prevent symptoms?Will I have to take medication for the rest of my life?What happens if I stop treatment?For More InformationWeb LinksMultimediaSynonyms and KeywordsAuthors and EditorsShould I see my health care provider if I have these symptoms?Call your health care provider if you have any symptoms of gastroesophageal reflux disease (GERD) that occur frequently, disrupt your sleep, interfere with work or other activities, or are not relieved by taking nonprescription antacids.
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The effects of sertraline in patients with moderate and severe hepatic impairment have not been studied.
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IUDs start working right away and can be removed at any time.
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ORTHO EVRAВ® may be less effective in these women.
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No dosing adjustments are recommended in the presence of moderate CYP3A4 inhibitors (e.g., erythromycin, fluconazole, diltiazem and verapamil).
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A person who faints or passes out due to a heart rhythm disturbance may be in a life-threatening situation.
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ALS is one of a group of diseases known as motor neuron diseases.

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Traditionally, genetic tests have been available only through healthcare providers such as physicians, nurse practitioners, and genetic counselors.
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Like PMS, the symptoms of PMDD start 7-14 days before a woman's period and go away once the period starts.
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Some publications provide information on tests for cancer, cancer causes and prevention, cancer statistics, and NCI research activities.
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In the event of resedation, repeated doses may be administered at 20-minute intervals as needed.
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IN THIS ARTICLERingworm on Scalp OverviewRingworm on Scalp CausesRingworm on Scalp SymptomsWhen to Seek Medical CareExams and TestsRingworm on Scalp TreatmentSelf-Care at HomeMedicationsNext StepsFollow-upPreventionOutlookFor More InformationWeb LinksMultimediaSynonyms and KeywordsAuthors and EditorsPictures of Ringworm - Slideshow Next StepsFollow-upFor the infection to be completely cured, the hair needs to grow out.
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To minimize the systemic effects of intranasal corticosteroids, including FLONASE Nasal Spray, each patient should be titrated to the lowest dose that effectively controls his/her symptoms.
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To get into bed, back up to the edge of the bed, tighten your abdominal muscles, and lower yourself into bed with your legs.
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The NCI Web site provides online access to information on cancer, clinical trials, and other Web sites and organizations that offer support and resources for cancer patients and their families.
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CLARINEX-DВ® 24 HOUR Extended Release Tablets should generally be avoided in patients with hepatic insufficiency.

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If these measures don't reduce your symptoms, talk to your employer about retraining for a different position that would not involve exposure to your trigger.
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Use of gloves and other protective clothing to prevent skin contact is recommended.
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Prosopagnosia is not related to memory dysfunction, memory loss, impaired vision, or learning disabilities.
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The opacity will diminish gradually.
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The cause of rheumatoid arthritis is not known.
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Most of these allergic reactions were treated successfully with antihistamines or corticosteroids; however, up to 10% of vaccinees with these reactions were hospitalized.
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After intercourse, the diaphragm must be left in place for at least 6 hours after sex but not more than 24 hours.
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In postoperative studies, the duration of analgesia with IV or IM butorphanol was similar to morphine, meperidine and pentazocine when administered in the same fashion at equipotent doses (see Clinical Trials).
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Patients who develop unexplained elevations in CPK while receiving CUBICIN should be monitored more frequently.

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Bitter orange oil is used in foods, cosmetics, and aromatherapy products.
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Approximately 6% of deaths are in pregnant women, although only 1% of the population is pregnant.
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Simple anemia, hemolytic anemia, megaloblastic anemia and aplastic anemia have occurred but are uncommon.
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The “flu syndrome” may also appear if rifampin is taken irregularly by the patient or if daily administration is resumed after a drug free interval.
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Various ocular diseases and long-term use of topical corticosteroids have been known to cause corneal and scleral thinning.
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Treatments for sprains and strains are similar and can be thought of as having two stages.
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Only FORTOVASE should be used for the initiation of therapy that includes saquinavir as a sole protease inhibitor (see [#section-12 DOSAGE AND ADMINISTRATION]) since FORTOVASE soft gelatin capsules provide greater bioavailability and efficacy than INVIRASE capsules.
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It is classed as an ergot-type agonist and therefore has some potential toxicity.
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The iris is made up of muscular fibers that control the amount of light entering the pupil so that we can see clearly.

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Through Week 48, 6В subjects (2%) in the group receiving ZIAGEN 600В mg once daily (4В CDC classification C events and 2В deaths) and 10В subjects (3%) in the group receiving ZIAGEN 300В mg twice daily (7В CDC classification C events and 3В deaths) experienced clinical disease progression.
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The abnormal bone marrow cells may begin to grow out of control.
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Glucagon is often used on ambulances if intravenous lines cannot be started.
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Steady-state conditions in the serum are observed within 57 days of daily dosing.
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If you have not taken the pills daily as instructed and missed a menstrual period, or if you missed two consecutive menstrual periods, you may be pregnant.
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The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals.
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The decision whether to continue the patient on therapy with DUETACT should be guided by clinical judgment pending laboratory evaluations.
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In mice that became pregnant, no fetuses survived this dose.
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Yin and Yang represent the two extremes found in nature.

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Concomitant use of agents in the tricyclic antidepressant class (which includes Anafranil) with drugs that can inhibit cytochrome P450 2D6 may require lower doses than usually prescribed for either the tricyclic antidepressant agent or the other drug.
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Cases of cardiomyopathy have been reported in patients treated with clozapine.
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If the pain is mild, the person may continue to move the knee joint.
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Some people lose just a few patches of hair, then the hair regrows, and the condition never recurs.
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This summary section refers to specific treatments under study in clinical trials, but it may not mention every new treatment being studied.
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In patients receiving opioids, both the dose and duration of analgesia will vary substantially depending on the patient's opioid tolerance.
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Laboratory determinations of serum levels of isosorbide dinitrate and its metabolites are not widely available, and such determinations have, in any event, no established role in the management of isosorbide dinitrate overdose.
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Cisatracurium undergoes organ-independent Hofmann elimination (a chemical process dependent on pH and temperature) to form the monoquaternary acrylate metabolite and laudanosine, neither of which has any neuromuscular blocking activity (see Pharmacokinetics - Metabolism section).
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In general, contact the doctor if you experience the following:Cough is associated with a fever and sputum productionCough fails to get better after other symptoms go away or lessenCough changes in characterTrial therapy shows no signs of reducing the coughYou begin coughing up bloodCough interferes with the activities of daily living or sleep cyclesCall your doctor immediately if you have shortness of breath or difficulty breathing.

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Up to 70% of all women get mild to moderate symptoms during the first three months (first trimester) of pregnancy.
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Routine determinations of serum T4 and/or TSH is strongly advised in neonates in view of the deleterious effects of thyroid deficiency on growth and development.
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Three terms are fetal alcohol effects (FAE), alcohol-related neurodevelopmental disorder (ARND), and alcohol-related birth defects (ARBD).
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The physician should consider contacting a poison control center for additional information on the treatment of any overdose.
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IN THIS ARTICLEIs birth control right for me?What type of birth control is best for me? Does my situation in life affect my choice of birth control?How do I prevent getting or spreading sexually transmitted diseases?Do I want a permanent form of birth control?What are the chances of a pregnancy if my current method of birth control is not used or fails? Should my partner and I consider using 2 forms of birth control (such as a male condom and birth control pills) at the same time?Which form of birth control can I afford?What birth control methods are available without seeing my doctor?What birth control methods are available from my health care provider?What will I do if I become pregnant and I don't want to be?For More InformationWeb LinksSynonyms and KeywordsAuthors and EditorsWhat are the chances of a pregnancy if my current method of birth control is not used or fails? Should my partner and I consider using 2 forms of birth control (such as a male condom and birth control pills) at the same time?Each birth control method has a failure rate.
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It often involves severe ulcers of the mouth and lips, cuts and scarring of the lining of the eye and eyelids, and skin blisters.
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Influenza viruses are small RNA viruses that infect many mammals, including humans, birds, and swine.
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This is an infection, and often there is a fever present.
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Stay off your feet as much as possible for a couple of days.