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Author Topic: Phosphagenics To Commence Phase 1b Transdermal Insulin Clinical Trial In Second Quarter  (Read 2982 times)
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« Reply #135 on: July 31, 2010, 03:40:42 AM »

It can make you feel many different emotions at the same time, especially confusion.
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A determination of whether or not a reported event met criterionВ 1 or 2 above was made by the Suicide Monitoring Board (SMB), a group of experts blinded to patient data.
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Strong inhibitors of CYP3A4 and P-gp significantly decrease the metabolism of sirolimus and increase sirolimus concentrations, while strong inducers of CYP3A4 and P-gp significantly increase the metabolism of sirolimus and decrease sirolimus concentrations.
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This will reduce the risk that the sex partners will develop serious complications from gonorrhea, and will also reduce the person’s risk of becoming re-infected.
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Cefoxitin exhibits in vitro minimum inhibitory concentrations (MIC’s) of 8 μg/mL or less for aerobic microorganisms and 16 μg/mL or less for anaerobic microorganisms against most (≥ 90%) strains of the following microorganisms; however, the safety and effectiveness of cefoxitin in treating clinical infections due to these microorganisms have not been established in adequate and well-controlled clinical trials.
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An additional dose of SINGULAIR should not be taken within 24 hours of a previous dose.
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When this publication was prepared, the NIDDK included the most current information available.
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« Reply #136 on: July 31, 2010, 11:48:13 AM »

If a woman's symptoms persist despite therapy for PMDD, a health care practitioner may suggest a different medication or treatment.
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IN THIS ARTICLEProgressive Supranuclear Palsy OverviewProgressive Supranuclear Palsy CausesProgressive Supranuclear Palsy SymptomsWhen to Seek Medical CareExams and TestsProgressive Supranuclear Palsy TreatmentSelf-Care at HomeMedical TreatmentMedicationsNext StepsFollow-upPreventionOutlookSupport Groups and CounselingFor More InformationWeb LinksSynonyms and KeywordsAuthors and EditorsProgressive Supranuclear Palsy TreatmentAt present, there is no cure for progressive supranuclear palsy.
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An electrocardiogram (EKG) is a screening test to look for electrical abnormalities in the heart.
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Ketoconazole also decreases ACTH induced corticosteroid serum levels at similar high doses.
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Aside from patients who present with an acute poisoning that requires short-term intervention, most patients with encephalopathy will need life-long care and monitoring.
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Sevoflurane is metabolized by cytochrome P450 2E1, to hexafluoroisopropanol (HFIP) with release of inorganic fluoride and CO2. Once formed HFIP is rapidly conjugated with glucuronic acid and eliminated as a urinary metabolite.
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« Reply #137 on: July 31, 2010, 11:15:40 PM »

Monoamine oxidase inhibitors (MAOIs) are the oldest class of antidepressant medications.
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The risk for CPM is greater if the serum (blood) sodium was consistently low for at least 2 days before correction.
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Men should also practice effective birth control while taking the drug.
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A patient with a pacemaker, prosthetic joint, stent, surgical clips, mechanical heart valve, or other metallic devices in his or her body might not be eligible for an MRA depending on the type of metallic device.
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The possibility that a woman of childbearing potential may be pregnant at the time of institution of therapy should be considered.
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The purpose of a rehabilitation program is to help the alcoholic accept the disease, begin to develop skills for sober living, and get enrolled in ongoing treatment and self-help programs.
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The mechanism of the antihypertensive effects of beta-blocking agents has not been elucidated.
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Drink plenty of fluids and mix each 5.5 gram dose of PrevaliteВ® (Cholestyramine for Oral Suspension, USP) in at least 2 to 3 ounces of fluid before taking.
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It does not increase total sleep time or decrease the number of awakenings throughout the night.
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« Reply #138 on: August 01, 2010, 08:03:05 AM »

Because constipation can be a symptom of a wide variety of problems, treatment depends on identifying the cause, as well as determining how severe and long-lasting it has been.
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At approximately 12 times the estimated human exposure, didanosine was slightly toxic to female rats and their pups during mid and late lactation.
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Another slight delay then occurs, allowing blood to return to the upper chambers of the heart, refilling the heart for the next cycle.
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IN THIS ARTICLEPremenstrual Syndrome (PMS) OverviewPremenstrual Syndrome (PMS) CausesPremenstrual Syndrome (PMS) SymptomsWhen to Seek Medical CareExams and TestsPremenstrual Syndrome (PMS) TreatmentSelf-Care at HomeMedicationsOther TherapyNext StepsPreventionOutlookSupport Groups and CounselingAuthors and EditorsViewer Comments: Premenstrual Syndrome (PMS) - Effective TreatmentsMedicationsPMS treatment Anti-inflammatories: These drugs prevent the body from producing prostaglandins, which have been suggested as a cause of PMS.
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Sodium phenylbutyrate is an off-white crystalline substance which is soluble in water and has a strong salty taste.
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Young children may swallow drugs by accident because of their curiosity about medications they may find.
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The side effects of drugs like cyclosporine can include high blood pressure, nausea, vomiting, kidney problems, headaches, tingling or numbness, and a possible increased risk of cancer and infections.
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« Reply #139 on: August 01, 2010, 04:40:36 PM »

The enzyme aromatase converts androgens (hormones that control male characteristics) to estrogens.
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Research has shown that the number of copies of the gene encoding EGFR is a good predictor of outcome of treatment with panitumumab.
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Other names for this condition include: Duane's Retraction Syndrome (or DR syndrome), Eye Retraction Syndrome, Retraction Syndrome, Congenital retraction syndrome and Stilling-Turk-Duane Syndrome.
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After its introduction in 1988, fluoxetine quickly became popular and by 1990 was the most-prescribed antidepressant in the US.
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When treating a pregnant woman with fluoxetine during the third trimester, the physician should carefully consider both the potential risks and benefits of treatment (see[#section-13 DOSAGE AND ADMINISTRATION]). Physicians should note that in a prospective longitudinal study of 201 women with a history of major depression who were euthymic at the beginning of pregnancy, women who discontinued antidepressant medication during pregnancy were more likely to experience a relapse of major depression than women who continued antidepressant medication.
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However, for some people this may mean cutting out healthy foods, such as fruits and vegetables, whole grains, and milk products.
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Clinical trials have not revealed any evidence of the potential for abuse, tolerance or physical dependence; however, systematic studies in humans designed to evaluate these effects have not been performed.
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The blood and fluid raise the macula from its normal place at the back of the eye.
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Such depletion usually develops slowly as a consequence of prolonged therapy with oral diuretics, primary or secondary hyperaldosteronism, diabetic ketoacidosis, severe diarrhea, or inadequate replacement of potassium in patients on prolonged parenteral nutrition.
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« Reply #140 on: August 02, 2010, 12:53:11 AM »

For more complete information about AVELOX request full prescribing information from your health care professional, pharmacist, or visit our website at www.
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Many people on dialysis have trouble sleeping at night because of aching, uncomfortable, jittery, or “restless” legs, called restless leg syndrome.
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If an individual appears to be intoxicated with alcohol to a degree that is radically disproportionate to the amount of alcohol in his or her blood the use of barbiturates should be suspected.
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AEROBID is also indicated for asthma patients who require systemic corticosteroid administration, where adding AEROBID may reduce or eliminate the need for the systemic corticosteroids.
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If the neutrophils drop to between 2500 and 1600/cu.
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See the disclaimer at the bottom of the comments page.
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Photograph courtesy of William Smock, MD.
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Stem cells (immature blood cells) are removed from the blood or bone marrow of the patient or a donor and are frozen and stored.
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« Reply #141 on: August 02, 2010, 09:21:20 AM »

Baseline CT findings, including the presence of ischemic changes involving more than one third of a hemisphere, have not been predictors of responses to treatment with rtPA when the agent is administered within the 3-hour treatment window.
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It is important to keep any follow-up appointments or tests.
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Any intracardiac conduction delay attributable to high concentrations of norpropoxyphene may be of relatively long duration.
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In addition, treatment of increased intracranial pressure may result in a decline in arterial blood pressure.
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Therapeutic shunting, which involves surgically inserting a draining tube from the spinal fluid space in the lower spine into the abdominal cavity, may be needed to remove excess fluid and relieve pressure.
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« Reply #142 on: August 02, 2010, 05:52:32 PM »

Note: In addition to REBETOLВ®3 (ribavirin) Capsules, Schering Corporation also markets REBETRONВ®4. REBETRON is a copackaged combination therapy containing REBETOL (ribavirin, USP) and INTRON A (interferon alfa-2b, recombinant) Injection.
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Therefore, dosage modification in patients with liver disease may not be necessary.
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There is a linear correlation between plasma quinaprilat clearance and creatinine clearance.
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Some studies have suggested that when compared to a low fat diet, people on the Mediterranean diet have had a greater decrease in body weight, greater improvements in lowering blood pressure and cholesterol levels, and improvement in other markers of heart disease; all of which are important in evaluating and treating metabolic syndrome.
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Delayed reactions, usually involving the skin, may uncommonly occur within 2-3 days (range 1-7 days) after the administration of contrast (see [#section-9.1 PRECAUTIONS-General).
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There has been one report of a fetal fatality after maternal exposure to idarubicin during the second trimester.
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You may be told to avoid food and fluids for 8 hours before the test.
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Your active involvement in treating this disease is vitally important.
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Do not chew, divide or crush tablets.
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« Reply #143 on: August 03, 2010, 02:05:37 AM »

Pimozide — Clinical studies of pimozide with other antidepressants demonstrate an increase in drug interaction or QTc prolongation.
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Because butorphanol may increase the work of the heart, especially the pulmonary circuit, the use of butorphanol in patients with acute myocardial infarction, ventricular dysfunction, or coronary insufficiency should be limited to those situations where the benefits clearly outweigh the risk (see CLINICAL PHARMACOLOGY).
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Weakness may be mild and limited to certain muscle groups, or more severe and affect the arms and legs.
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Clinical trials are taking place in many parts of the country.
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Dosage should be reduced in the elderly or debilitated because these patients may be more sensitive to barbiturates.
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When used on intertriginous or flexor areas, or on the face, this may occur even with short-term use.
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This consists of warm soaks, proper shoes, and frequent cleaning of the nail.
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The treatment of schizophrenia may be better understood in terms of phases: acute psychotic episode, treatment of co-occurring conditions, relapse prevention and maintenance [4]. In all phases anti-psychotics are the keystone of treatment.
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« Reply #144 on: August 03, 2010, 10:20:53 AM »

Symptoms indicating severe illness require emergency treatment.
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Insulin requirements may be reduced in the presence of drugs that lower blood glucose or affect how your body responds to insulin, such as oral antidiabetic agents, salicylates (for example, aspirin), sulfa antibiotics, alcohol, certain antidepressants and some kidney and blood pressure medicines.
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Routine screening for hemochromatosis in the general population has undergone considerable debate.
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Numbness or tingling: When a joint swells, it can pinch the nerves of sensation that pass next to it.
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Discontinue EPZICOM as soon as a hypersensitivity reaction is suspected.
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STORE AT ROOM TEMPERATURE 15°C – 30°C (59°F – 86°F).
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Respiratory syncytial virus usually needs just treatment of the symptoms.
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In the somewhat larger patient population exposed to benazepril monotherapy in U.S. trials, the same abnormalities were reported, together with scattered accounts of hyponatremia, melena, electrocardiographic changes, leukopenia, eosinophilia, and proteinuria.
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Corticosteroids, such as prednisone and prednisolone, are the mainstay of treatment of sarcoidosis.
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« Reply #145 on: August 03, 2010, 06:45:38 PM »

Surfaces should be thoroughly dried after cleaning.
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However, effective medications are available for those whose symptoms interfere with daily activities.
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These symptoms will gradually wear off be the end of the day.
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The program is implemented in kindergarten, 1st and 2nd grades and provides each class with a Teacher Guide containing the 8-lesson curriculum, a DVD (which illustrates the program in action), puzzles, exercise equipment, reading materials, and play foods.
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In these cases, the good eye can be patched to strengthen vision in the microphthalmic eye.
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Mandl KD, Stack AM, Fleisher GR.
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The dose does not need to be adjusted in the elderly or in people with decreased kidney function.
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Fortunately, people with herpes can have healthy and fulfilling relationships despite their disease.
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« Reply #146 on: August 04, 2010, 02:49:04 AM »

This problem is made worse because people with Prader-Willi syndrome use fewer calories than those without the syndrome, since they have less muscle mass.
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For patients requiring a single injection from multiple vials of BravelleВ®, up to 6 vials can beВ В В В В В В В reconstituted with 1 mL of Sterile Saline for Injection, USP.
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If blood from the uterus pools in the vaginal area, blood clots of varying sizes may form.
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An ASD is a hole in the part of the septum that separates the atria, the upper chambers of the heart.
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Hypersensitivity to levothyroxine itself is not known to occur.
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Keep track of the number of pads used and passage of clots and tissue.
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Oral contraceptives should be discontinued if there is unexplained partial or complete loss of vision; onset of proptosis or diplopia; papilledema; or retinal vascular lesions.
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MUCOMYST should not be placed directly into the chamber of a heated (hot pot) nebulizer.
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« Reply #147 on: August 04, 2010, 11:07:27 AM »

This includes, for example, seeing colors abnormally or blurred vision.
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Allergic reactions may occur as a result of sensitivity either to local anesthetic agents or to the methylparaben used as a preservative in the multiple dose vials.
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Although uncommon, in some cases, complications such as pain, infection, skin ulcers, and blood clots can develop.
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This would increase the likelihood that clinicians will take advantage of that PCCS.
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Human contact with sea urchins is either accidental or intentional.
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The knowledge gained from these fundamental studies provides the foundation for understanding abnormal brain development and offers hope for new ways to treat and prevent developmental brain disorders such as Dandy-Walker Syndrome.
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Before 2009, swine influenza predominately affected swine and was not transmitted often or easily to people.
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« Reply #148 on: August 04, 2010, 08:02:17 PM »

Your health care professional should tell you about the proper handling and disposal of all syringes and needles and the importance of not reusing any syringes or needles.
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Following oral administration, when postural hypotension has occurred, it has been transient and is uncommon when the recommended starting dose and titration increments are closely followed (see [#section-10 DOSAGE AND ADMINISTRATION]). Symptomatic postural hypotension is most likely to occur 2 to 4 hours after a dose, especially following the use of large initial doses or upon large changes in dose.
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Subsequent cycles consisted of injections onceВ weekly for 3В consecutive weeks out of every 4В weeks.
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In the other 95%, the cause is not known.
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The normal platelet count ranges between 150,000 and 450,000 per microliter (one-millionth of a liter).
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Age, Gender, and Race: PA clearance decreases with increasing patient age, in part due to concurrent decreases in renal function.
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Intramuscular— The usual recommended single dose for IM administration is 2 mg in patients who will be able to remain recumbent, in the event drowsiness or dizziness occurs.
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Pufferfish Poisoning OverviewThe poison found in pufferfish, blowfish, balloon fish, toads, sunfish, porcupine fish, toadfish, globefish, and swellfish is a tetrodotoxin.
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Glimepiride and glipizide have similar metabolic pathways and are mediated by CYP2C9; therefore, drug-drug interaction between pioglitazone and glimepiride is considered unlikely.
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« Reply #149 on: August 05, 2010, 04:45:38 AM »

If you are oligemic (have a blood deficiency in your body), levels of blood urea nitrogen (BUN, a nonprotein nitrogen compound in the blood) and creatinine (a substance in your urine) are also increased.
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The possibility of rapid emergence of resistant meningococci restricts the use of RIFADIN to short-term treatment of the asymptomatic carrier state.
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Although MRA is less reliable than CA for the detection of smaller aneurysms, it should be a reasonable screening tool for disorders like Ehlers-Danlos syndrome in which the ICA is often the site of aneurysm formation and the risk of CA is high.
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Although the term peripheral vascular disease can include any disorder that affects any of the blood vessels, it often is used as a synonym for peripheral artery disease.
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The vaccinia (smallpox) vaccine and vaccinia immune globulin (VIG) are available only through the CDC and state health agencies.
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Some of the commonly recommended methods for the evaluation of lactose intolerance will be discussed this section.
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Support groups provide reassurance, motivation, and inspiration.
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Although another side effect known as serum sickness (characterized by skin lesions, fever, pain in the joints, and swollen lymph glands) is common when horse serum is used to treat rattlesnake bites, it is uncommon when used to treat black widow spider bites (probably because of the low dose needed for relief).
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