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No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
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These changes occur within the first week after treatment, as do decreases in serum calcium levels, and are consistent with an antiresorptive pharmacologic action.
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Eye abnormalities occur in up to 95 percent of people with Noonan syndrome.
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This action is antagonized by acetylcholinesterase inhibitors such as neostigmine.
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Loss of deep–tendon reflexes, foot drop, ataxia, and paralysis have been reported with continued administration.
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The first man to break the four-minute mile, he ran 3:59.4 on May 6, 1954, at a meet in Oxford, England.

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In the omeprazole/clarithromycin/amoxicillin triple-therapy clinical trials, 84.9%В (157/185) of the patients who had pretreatment amoxicillin susceptible MICs (<В 0.25В Вµg/mL) were eradicated of H. pylori and 15.1% (28/185) failed therapy.
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Alzheimer's disease begins with a mild, slowly worsening memory loss.
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Also, some people test positive for rheumatoid factor, yet may never develop the disease.

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Ursodiol at oral doses of up to 2,700 mg/kg/day (16,200 mg/m2/day, 29 times the recommended maximum human dose based on body surface area) was found to have no effect on fertility and reproductive performance of male and female rats.
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They are bound to plasma and tissue proteins to a varying degree and binding increases directly as a function of lipid solubility.
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In most cases, symptoms are either totally gone, or very much improved, within eight to 10 weeks.
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Bicarbonate tablets (Alka-Seltzer, Bromo-Seltzer) are put into a glass of water.
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Peak circulating levels of sunitinib are generally observed between 6–12 hours post-dosing.
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Elimination - Evidence that the Css and AUC for CMI and DMI may increase disproportionately with increasing oral doses suggests that the metabolism of CMI and DMI may be capacity limited.
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Generally, any inflammation of the outer ear canal, such as infections, allergies, or skin conditions, can lead to swimmer's ear.

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Because the safety of duloxetine in infants is not known, nursing while on Cymbalta is not recommended.
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The National Institute of Neurological Disorders and Stroke (NINDS) conducts research relating to myoclonus in its laboratories at the National Institutes of Health (NIH) and also supports additional research through grants to major medical institutions across the country.
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Fatty degenerative changes of the liver were found in rats following longer durations of administration of propafenone HCl at a dose of 270 mg/kg/day (about 3 times the MRHD on a mg/m2 basis.
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These changes increase the risk for dangerous ventricular arrhythmias and sudden cardiac arrest.
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The NIDDK is part of the National Institutes of Health of the U.S. Department of Health and Human Services.
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Signs of infection are fever, increasing redness, swelling, severe pain of the finger, or even discharge of pus and a foul smell from the surgery site.
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About 1 in 200 POP users will get pregnant in the first year if they all take POPs perfectly (that is, on time, every day).

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Ribavirin, used in combination with interferon for the treatment of HCV infection, decreased the anti-HIV potency of abacavir/lamivudine reproducibly by 2- to 6-fold in cell culture.
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Smith-Lemli-Opitz syndrome is a developmental disorder that affects many parts of the body.
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Ifosfamide exhibits dose-dependent pharmacokinetics in humans.
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Both tolterodine and the 5-hydroxymethyl metabolite exhibit a high specificity for muscarinic receptors, since both show negligible activity or affinity for other neurotransmitter receptors and other potential cellular targets, such as calcium channels.
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A liver biopsy is not necessary for diagnosis, but it helps grade the disease severity and stage the amount of liver damage.
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The pulp, the innermost layer, contains the blood supply that nourishes the tooth as well as nerve fibers that provide pain and temperature sensation.
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On a body surface area basis, the doses used were up 55 times, 33 times, and 0.15 times, respectively, the MRHDD.

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Cardiac catheterization is a procedure used to diagnose and treat certain heart conditions.
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A pregnant woman can also administer (give) a nasal spray vaccine (LAIV).
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The terminal half-life, oral clearance and apparent volume of distribution were 6.2 В± 1.8 hours, 5.9 В± 1.7 mL/min/kg, and 3.0 В± 0.4 L/kg, respectively.
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Imatinib inhibits CYP2D6, which is another drug-metabolizing enzyme in the liver.
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Treatment consists of discontinuation of terbutaline sulfate injection together with appropriate symptomatic therapy.
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Following oral administration of a single 150 mg dose of bupropion, there were no statistically significant differences in Cmax, half-life, Tmax, AUC or clearance of bupropion or its active metabolites between smokers and nonsmokers.
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IN THIS ARTICLEShoulder Separation OverviewShoulder Separation CausesShoulder Separation SymptomsWhen to Seek Medical CareExams and TestsShoulder Separation TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upOutlookMultimediaSynonyms and KeywordsAuthors and EditorsExams and TestsThe diagnosis for shoulder separation is made based on careful history taking and physical examination findings.
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This test uses sound waves to create a moving picture of the heart.

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Certain movements of the head or neck or external pressure to the neck may trigger these headaches in some patients.
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Hypersensitivity reactions represent the most frequent spontaneously-reported adverse events in worldwide postmarketing experience with nitrofurantoin formulations.
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Few were placebo-controlled studies, and most assessed symptoms by using the Kupperman index, a scale that combines measures of hot flashes, insomnia, and depression but not vaginal dryness.
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Do not force anything into the child's mouth.
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See also [#section-7.3 PRECAUTIONS, Drug Interactions].)В  The bioavailability of SKELID is decreased 80% by calcium, when calcium and SKELID are administered at the same time, and 60% by some aluminum- or magnesium-containing antacids, when administered 1 hour before SKELID.
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There are no adequate and well-controlled studies of systemic acyclovir in pregnant women.
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Mifepristone is rapidly absorbed, with peak circulating levels occurring approximately 90 minutes after ingestion.

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Heart failure is a condition in which the heart can’t pump blood the way it should.

The baby is seemingly healthy without any sign of distress or significant illness prior to the incident.

Parkinson's disease causes a 4- to 6-Hz resting tremor in the arms and legs that responds to the use of anticholinergics and a combination of carbidopa and levodopa.

Exposure to temperatures above 25В°C/77В°F during transport and storage will lead to minor losses in moisture content.

Propulsive peristaltic waves in the colon are decreased, while tone is increased to the point of spasm.

The term polycythemia vera typically refers to primary polycythemia, and is also called polycythemia rubra vera (PRV), or erythremia.

Hypotension (low blood pressure) due to many factors (for example, blood loss and blood pressure medications) may result in encephalopathy with symptoms of fainting, weakness and altered mental status.

A confirmatory test that is more specific may be available.

They include people who have had bleeding in the brain (a type of stroke), recent brain surgery, or bleeding from the gastrointestinal tract.

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ALFENTA infusions should be discontinued at least 10-15 minutes prior to the end of surgery during general anesthesia.
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IN THIS ARTICLEPsoriatic Arthritis OverviewPsoriatic Arthritis CausesPsoriatic Arthritis SymptomsWhen to Seek Medical CareQuestions to Ask the DoctorExams and TestsPsoriatic Arthritis TreatmentSelf-Care at HomeMedical TreatmentMedicationsSurgeryOther TherapyNext StepsFollow-upPreventionOutlookSupport Groups and CounselingFor More InformationWeb LinksMultimediaSynonyms and KeywordsAuthors and EditorsViewer Comments: Psoriatic Arthritis - Describe Your ExperienceMedical TreatmentInitial treatment consists of NSAIDs for your joints and creams or ointments for your skin.
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The blood pressure may need to be supported with medications until the breathing status improves.
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YAZ may also be taken to treat premenstrual dysphoric disorder (PMDD) if you choose to use the Pill for birth control.
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Follow wound care guidelines.
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It inhibits de novopurine biosynthesis by pseudo-feedback inhibition of glutamine-5-phosphoribosylpyrophosphate amidotransferase—the first enzyme unique to the de novo pathway for purine ribonucleotide synthesis.

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The effectiveness of fluoxetine for the treatment of bulimia was demonstrated in two 8 week and one 16 week multicenter, parallel group studies of adult outpatients meeting DSM-III-R criteria for bulimia.
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These people may have silent LQTS.
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It can be seen in the fingers when the arms are outstretched.
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IN THIS ARTICLEOrchitis OverviewOrchitis CausesOrchitis SymptomsWhen to Seek Medical CareExams and TestsOrchitis TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upPreventionOutlookFor More InformationWeb LinksSynonyms and KeywordsAuthors and EditorsPreventionChoose not to have intercourse in high-risk situations where you may be exposed to sexually transmitted diseases (STDs).
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Over time, the intervals between follow-up appointments will increase.
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Following guidelines can reduce or eliminate toxic mercury exposures.
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Those laboratory tests which are abnormal at the time of initiation of minoxidil therapy, such as urinalysis, renal function tests, EKG, chest x-ray, echocardiogram, etc.
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In contrast, women who were physically but not sexually abused as children had a rate of trauma later in life that was similar to that of people who were not physically abused.
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This can occur at the onset of type 2 diabetes as well, especially in young people.

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Another statin trial including elderly people (70 years of age) found no effect on total stroke rate but did find a 25% reduction in TIAs.
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Take care not to injure the finger even more.
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A complete blood count is a non-specific test.
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Dosages and schedules must be adjusted to prevent life-threatening cytopenias whenever these adverse reactions are observed.
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Sunscreens will not protect the patient against photosensitivity reactions.
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They can also activate a group of proteins called complement that are also part of the immune system.
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If a favorable response does not occur promptly, use of fluticasone propionate ointment, 0.005% should be discontinued until the infection has been adequately controlled.
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These serious events may occur without warning.
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The NIAMS also funds many lupus researchers across the United States.

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Cockayne syndrome can be divided into subtypes, which are distinguished by the severity and age of onset of symptoms.
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IN THIS ARTICLEBroken Shoulder Blade OverviewBroken Shoulder Blade CausesBroken Shoulder Blade SymptomsWhen to Seek Medical CareExams and TestsBroken Shoulder Blade TreatmentSelf-Care at HomeMedical TreatmentSurgeryOther TherapyNext StepsFollow-upPreventionOutlookSynonyms and KeywordsAuthors and EditorsNext StepsFollow-upBroken shoulder blades should receive ongoing treatment by an orthopedic surgeon or sports medicine specialist to ensure proper healing.
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IN THIS ARTICLEShark Bite and Shark Attack OverviewShark Bite SymptomsWhen to Seek Medical CareExams and TestsShark Bite and Shark Attack TreatmentSelf-Care at HomeMedical TreatmentNext StepsFollow-upPreventionOutlookMultimediaSynonyms and KeywordsAuthors and EditorsExams and TestsA person may not always know whether the wound came from a shark or another fish, such as a barracuda.
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The list includes: cleft palate, usually of the soft palate (the roof of the mouth nearest the throat which is behind the bony palate); heart problems; similar faces (elongated face, almond-shaped eyes, wide nose, small ears); learning difficulties; eye problems; feeding problems that include food coming through the nose (nasal regurgitation) because of the cleft palate; middle-ear infections ([javascript:openglossarywindow('102'); otitis media]); hypoparathyroidism (low levels of the parathyroid hormone that can result in seizures); immune system problems which make it difficult for the body to fight infections; weak muscles; short height; curvature of the spine (scoliosis); and tapered fingers.
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NOTE: It is extremely common for an intoxicated person to vomit once.
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One meta analysis of approximately 47gm soy protein/day showed a 9.3% reduction in total cholesterol, 12.9% decrease in LDL, and 13.3% diminution in triglycerides.
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The incidence of adverse events in placebo-controlled clinical trials was not affected by age or weight of the patients, duration of headache prior to treatment, presence of aura, use of prophylactic medications, or tobacco use.
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Resistance of HSV and VZV to acyclovir can result from qualitative or quantitative changes in the viral TK or DNA polymerase.
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After a minute, the filter paper is removed and the amount of wetting is measured.

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In the circulatory system, blood carrying oxygen from the lungs is normally pumped by the heart into the arteries at high pressure.
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Recurrent thymoma and thymic carcinoma is cancer that has recurred (come back) after it has been treated.
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Upon removal from refrigeration to room temperature storage conditions (25В°C/77В°F), use NIMBEX Injection within 21 days even if rerefrigerated.
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Paroxetine, a potent inhibitor of CYP2D6, increased average steady-state plasma concentrations of ranolazine 1.2-fold.
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A lipoprotein analysis (including LDL-C determination) should be carried out once a year.
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It is recommended that postpartum MIRENAВ  insertion be delayed until uterine involution is complete to decrease perforation risk.
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The heart is an electrically-innervated, muscular pump that pushes blood throughout the body through blood vessels.
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Automobile manufacturers have modified vehicles to include devices that add tension to your seat belt during a collision and have devised a multitude of airbag devices to cushion vehicle occupants during crashes.
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For the reversal of the sedative effects of benzodiazepines administered for conscious sedation, the recommended initial dose of flumazenil injection is 0.2 mg (2 mL) administered intravenously over 15 seconds.

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A new cycle of therapy should not begin until the toxicity has recovered to NCI grade 1 or less.
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In Shakespeare's tragic play, Macbeth, Lady Macbeth's famous sleepwalking scene ("out, damned spot") is ascribed to her guilt and resulting insanity as a consequence of her involvement in the murder of her father-in-law.
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Parents may note symptoms as early as infancy, although the typical age of onset is before 3 years of age.
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Just as petrol is the fuel, or energy source for a car, Prana is the fuel for all energy, in fact, any motion.
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Call your doctor if the burning feeling is severe or lasts for more than 1 week.
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Chronic myelogenous leukemia is a disease in which too many white blood cells are made in the bone marrow.
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Grating (crepitus) of the kneecap against the thigh bone (femur) during flexing and extending the knee can sometimes cause a pain response.
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Pain relievers: Anti-inflammatories such as ibuprofen (for example, Advil) may help reduce pelvic pain.

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These studies demonstrated no evidence of teratogenic effects as a result of ipratropium bromide.
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These allergic reactions have been similar in nature and severity to those reported with other platinum-containing compounds, i.e., rash, urticaria, erythema, pruritus, and rarely bronchospasm and hypotension.
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This prevents A2 from increasing blood pressure.
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Currently, the National Institute of Drug Abuse's top research priority is the development of a medication useful in treating cocaine addiction.
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IN THIS ARTICLEHuman Bites OverviewHuman Bites CausesHuman Bites SymptomsWhen to Seek Medical CareExams and TestsHuman Bites TreatmentSelf-Care at HomeMedical TreatmentMedicationsNext StepsFollow-upPreventionOutlookSynonyms and KeywordsAuthors and EditorsMedical TreatmentMinor bites: A bite that just causes bruising or only scrapes the top layer of skin will not require much more than cleaning with soap and water, ice, and mild pain medication such as acetaminophen (Tylenol is one brand name).
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Before you change your calcium intake or exercise habits, it is important to discuss these lifestyle changes with your doctor to find out if they are safe for you.
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Concomitant therapy should be based on a patient's prior drug exposure.
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However, fetal toxicity consisting of delayed ossification of portions of the skeleton occurred at dose levels of 2.5 and 5 mg /kg /day in rats and at 2.5 mg/kg/day in rabbits.
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When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy).