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What Is Tramadol
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supernenko
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Posts: 4
What Is Tramadol
«
on:
June 24, 2010, 02:19:40 PM »
Tramadol is a synthetic analog of the phenanthrene alkaloid codeine and, as such, is an opioid and also a prodrug (codeine is metabolized to morphine, tramadol is converted to M-1 aka O-desmethyltramadol). Opioids are chemical compounds which act upon one or more of the human opiate receptors (the euphoria, addictive nature and respiratory depression are mainly caused by the Mu(?) 1 and 2 receptor. The opioid agonistic effect of tramadol and its major metabolite(s) are almost exclusively mediated by the substance's action at the ?-opioid receptor. This characteristic distinguishes tramadol from many other substances (including morphine) of the opioid drug class, which generally do not possess tramadol's degree of subtype selectivity.
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xandunn
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Posts: I am a geek!!
Re: What Is Tramadol
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Reply #1 on:
July 30, 2024, 04:53:24 PM »
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